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Cypellocarpin C

CAS# 294856-66-9

Cypellocarpin C

2D Structure

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Cypellocarpin C: 5mg $1012 In Stock
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Quality Control of Cypellocarpin C

3D structure

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Cypellocarpin C

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Chemical Properties of Cypellocarpin C

Cas No. 294856-66-9 SDF Download SDF
PubChem ID 10625791 Appearance Powder
Formula C26H32O11 M.Wt 520.53
Type of Compound Phenols Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(5-hydroxy-2-methyl-4-oxochromen-7-yl)oxyoxan-2-yl]methyl (4R)-4-(2-hydroxypropan-2-yl)cyclohexene-1-carboxylate
SMILES CC1=CC(=O)C2=C(C=C(C=C2O1)OC3C(C(C(C(O3)COC(=O)C4=CCC(CC4)C(C)(C)O)O)O)O)O
Standard InChIKey OUBDJJFZUQGQLU-ZHFYLPRNSA-N
Standard InChI InChI=1S/C26H32O11/c1-12-8-16(27)20-17(28)9-15(10-18(20)35-12)36-25-23(31)22(30)21(29)19(37-25)11-34-24(32)13-4-6-14(7-5-13)26(2,3)33/h4,8-10,14,19,21-23,25,28-31,33H,5-7,11H2,1-3H3/t14-,19+,21+,22-,23+,25+/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Cypellocarpin C

The dried leaves of Eucalyptus cypellocarpa.

Biological Activity of Cypellocarpin C

Description1. Cypellocarpin C shows potent in vitro antitumor-promoting activity, it also can suppress an in vivo two-stage carcinogenesis induced with nitric oxide and TPA on mouse skin.

Cypellocarpin C Dilution Calculator

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Cypellocarpin C Molarity Calculator

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Preparing Stock Solutions of Cypellocarpin C

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9211 mL 9.6056 mL 19.2112 mL 38.4224 mL 48.028 mL
5 mM 0.3842 mL 1.9211 mL 3.8422 mL 7.6845 mL 9.6056 mL
10 mM 0.1921 mL 0.9606 mL 1.9211 mL 3.8422 mL 4.8028 mL
50 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7684 mL 0.9606 mL
100 mM 0.0192 mL 0.0961 mL 0.1921 mL 0.3842 mL 0.4803 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Cypellocarpin C

[Studies on chemical constituents in fruits of Eucalyptus globulus].[Pubmed:17552153]

Zhongguo Zhong Yao Za Zhi. 2007 Mar;32(6):496-500.

OBJECTIVE: To study the chemical constituents in the fruits of Eucalyptus globulus Labill. METHOD: The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by IR, NMR and MS evidences. RESULT: Fifteen compounds were obtained and identified as beta-sitosterol (1), betulinic acid (2), stigmasterol (3), euscaphic acid (4), 2a-Hydroxybetulinic acid (5), macrocarpal B (6), macrocarpal A (7), oleanolic acid (8), 3,4,3'-O-trimethylellagic acid (9), 3-O-methylellagic acid 4'-O-(2"-O-acetyl )-alpha-L-rhamnopyranoside (10), camaldulenside (Cypellocarpin C, 11), 3-O-methylellagic acid 4'-O-alpha-L-rhamnopyranoside (12), 3-O-methylellagic acid (13), ellagic acid (14), and gallic acid (15). CONCLUSION: Compounds 4 and 5 from genera Eucalyptus, 1, 3 and 11 from plant E. globulus, and 6, 7, 9 and 15 from the fruits of E. globulus were isolated for the first time.

Cypellocarpins A-C, phenol glycosides esterified with oleuropeic acid, from Eucalyptus cypellocarpa.[Pubmed:11000030]

J Nat Prod. 2000 Sep;63(9):1253-7.

Three new phenol glycosides acylated with (+)-oleuropeic acid, cypellocarpins A (1), B (2), and C (3), along with seven known compounds, were isolated from the dried leaves of Eucalyptus cypellocarpa. Structures of the new compounds were determined on the basis of spectroscopic methods, including 2D NMR experiments and chemical degradation. These new compounds and a known related glucoside (7) showed potent in vitro antitumor-promoting activity in a short-term bioassay evaluating the inhibitory effect on Epstein-Barr virus early antigen activation induced by 12-O-tetradecanoyl phorbol 13-acetate (TPA). These compounds also suppressed an in vivo two-stage carcinogenesis induced with nitric oxide and TPA on mouse skin.

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