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13-Oxo-9E,11E-octadecadienoic acid

CAS# 29623-29-8

13-Oxo-9E,11E-octadecadienoic acid

Catalog No. BCN8173----Order now to get a substantial discount!

Product Name & Size Price Stock
13-Oxo-9E,11E-octadecadienoic acid: 5mg $322 In Stock
13-Oxo-9E,11E-octadecadienoic acid: 10mg Please Inquire In Stock
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13-Oxo-9E,11E-octadecadienoic acid: 500mg Please Inquire Please Inquire
13-Oxo-9E,11E-octadecadienoic acid: 1000mg Please Inquire Please Inquire
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Quality Control of 13-Oxo-9E,11E-octadecadienoic acid

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Chemical structure

13-Oxo-9E,11E-octadecadienoic acid

3D structure

Chemical Properties of 13-Oxo-9E,11E-octadecadienoic acid

Cas No. 29623-29-8 SDF Download SDF
PubChem ID 5283012 Appearance Powder
Formula C18H30O3 M.Wt 294.43
Type of Compound Lipids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (9E,11E)-13-oxooctadeca-9,11-dienoic acid
SMILES CCCCCC(=O)C=CC=CCCCCCCCC(=O)O
Standard InChIKey JHXAZBBVQSRKJR-KDFHGORWSA-N
Standard InChI InChI=1S/C18H30O3/c1-2-3-11-14-17(19)15-12-9-7-5-4-6-8-10-13-16-18(20)21/h7,9,12,15H,2-6,8,10-11,13-14,16H2,1H3,(H,20,21)/b9-7+,15-12+
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of 13-Oxo-9E,11E-octadecadienoic acid

The leaves of Artemisia argyi

Biological Activity of 13-Oxo-9E,11E-octadecadienoic acid

Description13-Oxo-9E,11E-octadecadienoic acid has antitumor activity.
In vitro

Screening and analysis of potential anti-tumor components from the stipe of Ganoderma sinense using high-performance liquid chromatography/time-of-flight mass spectrometry with multivariate statistical tool.[Reference: WebLink]

Journal of Chromatography A, 2017, 1487:162-167.

According to Chinese Pharmacopoeia 2015 edition, Ganoderma (Lingzhi) is a species complex that comprise of Ganoderma lucidum and Ganoderma sinense. The bioactivity and chemical composition of G. lucidium had been studied extensively, and it was shown to possess antitumor activities in pharmacological studies. In contrast, G. sinense has not been studied in great detail. Our previous studies found that the stipe of G. sinense exhibited more potent antitumor activity than the pileus.
METHODS AND RESULTS:
To identify the antitumor compounds in the stipe of G. sinense, we studied its chemical components by merging the bioactivity results with liquid chromatography-mass spectrometry-based chemometrics.The stipe of G. sinense was extracted with water, followed by ethanol precipitation and liquid–liquid partition. The resulting residue was fractionated using column chromatography. The antitumor activity of these fractions were analysed using MTT assay in murine breast tumor 4T1 cells, and their chemical components were studied using the LC-QTOF-MS with multivariate statistical tools. The chemometric and MS/MS analysis correlated bioactivity with five known cytotoxic compounds, 4-hyroxyphenylacetate, 9-oxo-(10E,12E)-octadecadienoic acid, 3-phenyl-2-propenoic acid, 13-Oxo-9E,11E-octadecadienoic acid and lingzhine C, from the stipe of G. sinense.
CONCLUSIONS:
To the best of our knowledge, 4-hyroxyphenylacetate, 3-phenyl-2-propenoic acid and lingzhine C are firstly reported to be found in G. sinense. These five compounds will be investigated for their antitumor activities in the future.

13-Oxo-9E,11E-octadecadienoic acid Dilution Calculator

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13-Oxo-9E,11E-octadecadienoic acid Molarity Calculator

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Preparing Stock Solutions of 13-Oxo-9E,11E-octadecadienoic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.3964 mL 16.982 mL 33.9639 mL 67.9279 mL 84.9098 mL
5 mM 0.6793 mL 3.3964 mL 6.7928 mL 13.5856 mL 16.982 mL
10 mM 0.3396 mL 1.6982 mL 3.3964 mL 6.7928 mL 8.491 mL
50 mM 0.0679 mL 0.3396 mL 0.6793 mL 1.3586 mL 1.6982 mL
100 mM 0.034 mL 0.1698 mL 0.3396 mL 0.6793 mL 0.8491 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Description

13-Oxo-9E,11E-octadecadienoic acid, an isomer of 9-oxo-ODA, is a potent PPARα activator derived from tomato juice. 13-Oxo-9E,11E-octadecadienoic acid decreases plasma and hepatic triglyceride in obese diabetic mice.

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