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Clopidol

CAS# 2971-90-6

Clopidol

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Quality Control of Clopidol

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Chemical structure

Clopidol

3D structure

Chemical Properties of Clopidol

Cas No. 2971-90-6 SDF Download SDF
PubChem ID 18087 Appearance Powder
Formula C7H7Cl2NO M.Wt 192
Type of Compound N/A Storage Desiccate at -20°C
Solubility DMSO : < 1 mg/mL (insoluble or slightly soluble)
Chemical Name 3,5-dichloro-2,6-dimethyl-1H-pyridin-4-one
SMILES CC1=C(C(=O)C(=C(N1)C)Cl)Cl
Standard InChIKey ZDPIZLCVJAAHHR-UHFFFAOYSA-N
Standard InChI InChI=1S/C7H7Cl2NO/c1-3-5(8)7(11)6(9)4(2)10-3/h1-2H3,(H,10,11)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Clopidol Dilution Calculator

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Clopidol Molarity Calculator

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Preparing Stock Solutions of Clopidol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.2083 mL 26.0417 mL 52.0833 mL 104.1667 mL 130.2083 mL
5 mM 1.0417 mL 5.2083 mL 10.4167 mL 20.8333 mL 26.0417 mL
10 mM 0.5208 mL 2.6042 mL 5.2083 mL 10.4167 mL 13.0208 mL
50 mM 0.1042 mL 0.5208 mL 1.0417 mL 2.0833 mL 2.6042 mL
100 mM 0.0521 mL 0.2604 mL 0.5208 mL 1.0417 mL 1.3021 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Clopidol

Development of an enzyme-linked immunosorbent assay for detection of clopidol residues in chicken tissues.[Pubmed:24395395]

J Sci Food Agric. 2014 Aug;94(11):2295-300.

BACKGROUND: Clopidol is mainly used for the prevention and treatment of coccidiosis, which poses a serious potential hazard to public health, in veterinary medicine. The aim of this study was to prepare monoclonal antibodies (mAbs) against Clopidol (CLOP) and develop an immunoassay for detecting CLOP residues in chicken tissues. After derivation, CLOP hapten was conjugated to carrier proteins to synthesize the artificial antigen, and immunized Balb/C mice were employed to screen mAbs. RESULTS: A sensitive hybridoma named C1G3 was screened out and two indirect competitive enzyme-linked immunosorbent assay (icELISA) standard curves were established. For the traditional two-step assay the linear range was from 0.06 to 98 ng mL(-1) , with half-maximal inhibitory concentration (IC50 ) and limit of detection (LOD) values of 2.76 ng mL(-1) and 0.03 ng mL(-1) respectively, while the rapid one-step icELISA had a working range from 0.08 to 102 ng mL(-1) , with IC50 and LOD values of 3.52 ng mL(-1) and 0.03 ng mL(-1) respectively. It was also indicated that a 10-fold dilution in chicken muscles gave an inhibition curve almost the same as that obtained in phosphate-buffered saline. When applied to spiking tests in chicken samples, the correlation coefficient (R(2) ) between concentrations added and measured was 0.9534. CONCLUSION: The results of this study suggest that the immunoassay described is a promising alternative for screening CLOP residues in biological matrices and is suitable for routine diagnostics.

Description

Clopidol is an organic compound that is used as in veterinary medicine, as a coccidiostat.

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