Oleic acid

CAS# 112-80-1

Oleic acid

2D Structure

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3D structure

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Oleic acid

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Chemical Properties of Oleic acid

Cas No. 112-80-1 SDF Download SDF
PubChem ID 445639 Appearance Oil
Formula C18H34O2 M.Wt 282.5
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility DMSO : ≥ 62.5 mg/mL (221.27 mM)
*"≥" means soluble, but saturation unknown.
Chemical Name (Z)-octadec-9-enoic acid
SMILES CCCCCCCCC=CCCCCCCCC(=O)O
Standard InChIKey ZQPPMHVWECSIRJ-KTKRTIGZSA-N
Standard InChI InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Oleic acid

The whole plants of Citrullus colocynthis (Linn.) Schrad.

Biological Activity of Oleic acid

Description1. Oleic acid and Linoleic acid show larvicidal effects against fourth instar larvae of Aedes aegypti L. (LC50 8.80, 18.20 and LC90 35.39, 96.33 ppm), Anopheles stephensi Liston (LC50 9.79, 11.49 and LC90 37.42, 47.35 ppm), and Culex quinquefasciatus Say (LC50 7.66, 27.24 and LC90 30.71, 70.38 ppm).

Oleic acid Dilution Calculator

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Oleic acid Molarity Calculator

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Preparing Stock Solutions of Oleic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.5398 mL 17.6991 mL 35.3982 mL 70.7965 mL 88.4956 mL
5 mM 0.708 mL 3.5398 mL 7.0796 mL 14.1593 mL 17.6991 mL
10 mM 0.354 mL 1.7699 mL 3.5398 mL 7.0796 mL 8.8496 mL
50 mM 0.0708 mL 0.354 mL 0.708 mL 1.4159 mL 1.7699 mL
100 mM 0.0354 mL 0.177 mL 0.354 mL 0.708 mL 0.885 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Oleic acid

Mosquito larvicidal activity of oleic and linoleic acids isolated from Citrullus colocynthis (Linn.) Schrad.[Pubmed:18688644]

Parasitol Res. 2008 Nov;103(6):1383-90.

In mosquito control programs, botanical origin may have the potential to be used successfully as larvicides. The larvicidal activity of crude acetone, hexane, ethyl acetate, methanol, and petroleum ether extracts of the leaf of Centella asiatica Linn., Datura metal Linn., Mukia scabrella Arn., Toddalia asiatica (Linn.) Lam, extracts of whole plant of Citrullus colocynthis (Linn.) Schrad, and Sphaeranthus indicus Linn. were assayed for their toxicity against the early fourth instar larvae of Culex quinquefasciatus (Diptera: Culicidae). The larval mortality was observed after 24 h exposure. All extracts showed moderate larvicidal effects; however, the highest larval mortality was found in whole plant petroleum ether extract of C. colocynthis. In the present study, bioassay-guided fractionation of petroleum ether extract led to the separation and identification of fatty acids; Oleic acid and linOleic acid were isolated and identified as mosquito larvicidal compounds. Oleic and LinOleic acids were quite potent against fourth instar larvae of Aedes aegypti L. (LC50 8.80, 18.20 and LC90 35.39, 96.33 ppm), Anopheles stephensi Liston (LC50 9.79, 11.49 and LC90 37.42, 47.35 ppm), and Culex quinquefasciatus Say (LC50 7.66, 27.24 and LC90 30.71, 70.38 ppm). The structure was elucidated from infrared, ultraviolet, 1H-nuclear magnetic resonance, 13C-NMR, and mass spectral data. This is the first report on the mosquito larvicidal activity of the reported isolated compounds from C. colocynthis.

Description

Oleic acid is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator.

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