Home >> Research Area >>Natural Products>>Alkaloids>> Dihydrocorynantheine

Dihydrocorynantheine

CAS# 4684-43-9

Dihydrocorynantheine

Catalog No. BCN3747----Order now to get a substantial discount!

Product Name & Size Price Stock
Dihydrocorynantheine: 5mg Please Inquire In Stock
Dihydrocorynantheine: 10mg Please Inquire In Stock
Dihydrocorynantheine: 20mg Please Inquire Please Inquire
Dihydrocorynantheine: 50mg Please Inquire Please Inquire
Dihydrocorynantheine: 100mg Please Inquire Please Inquire
Dihydrocorynantheine: 200mg Please Inquire Please Inquire
Dihydrocorynantheine: 500mg Please Inquire Please Inquire
Dihydrocorynantheine: 1000mg Please Inquire Please Inquire
Related Products
  • Hirsutine

    Catalog No.:BCN2758
    CAS No.:7729-23-9

Quality Control of Dihydrocorynantheine

Number of papers citing our products

Chemical structure

Dihydrocorynantheine

3D structure

Chemical Properties of Dihydrocorynantheine

Cas No. 4684-43-9 SDF Download SDF
PubChem ID 5316699 Appearance Cryst.
Formula C22H28N2O3 M.Wt 368.5
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name methyl (E)-2-[(3R)-3-ethyl-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate
SMILES CCC1CN2CCC3=C(C2CC1C(=COC)C(=O)OC)NC4=CC=CC=C34
Standard InChIKey NMLUOJBSAYAYEM-WODWAOHHSA-N
Standard InChI InChI=1S/C22H28N2O3/c1-4-14-12-24-10-9-16-15-7-5-6-8-19(15)23-21(16)20(24)11-17(14)18(13-26-2)22(25)27-3/h5-8,13-14,17,20,23H,4,9-12H2,1-3H3/b18-13+/t14-,17?,20?/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Dihydrocorynantheine

The bark of Corynanthe pachyceras

Biological Activity of Dihydrocorynantheine

Description1. Dihydrocorynantheine exhibits significant vasodilating activity against phenylephrine-induced contraction in rat thoracic aorta rings (IC(50) = 6.73 μg/mL), it also shows weak inhibitory action on KCl-induced contraction. 2. Dihydrocorynantheine shows pronounced activity against Leishmania major promastigotes (IC50 at the micromolar level) but no significant in vitro antiplasmodial activity (against chloroquinesensitive Plasmodium falciparum).
TargetsAntifection

Dihydrocorynantheine Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Dihydrocorynantheine Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Dihydrocorynantheine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7137 mL 13.5685 mL 27.137 mL 54.2741 mL 67.8426 mL
5 mM 0.5427 mL 2.7137 mL 5.4274 mL 10.8548 mL 13.5685 mL
10 mM 0.2714 mL 1.3569 mL 2.7137 mL 5.4274 mL 6.7843 mL
50 mM 0.0543 mL 0.2714 mL 0.5427 mL 1.0855 mL 1.3569 mL
100 mM 0.0271 mL 0.1357 mL 0.2714 mL 0.5427 mL 0.6784 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Dihydrocorynantheine

Macrophyllionium and macrophyllines A and B, oxindole alkaloids from Uncaria macrophylla.[Pubmed:21070010]

J Nat Prod. 2011 Jan 28;74(1):12-5.

An unusual oxindole alkaloid inner salt, macrophyllionium (1), and a pair of new tetracyclic oxindole alkaloids, macrophyllines A (2) and B (3), together with six known alkaloids, were isolated from the aerial parts of Uncaria macrophylla. Corynantheidine (8) exhibited moderate cytotoxicity against HL-60 and SW480 cells with IC(50) values of 13.96 and 23.28 muM, respectively. Dihydrocorynantheine (9) exhibited significant vasodilating activity against phenylephrine-induced contraction in rat thoracic aorta rings (IC(50) = 6.73 mug/mL). In addition, compounds 2, 6, and 9 showed weak inhibitory action on KCl-induced contraction.

Keywords:

Dihydrocorynantheine,4684-43-9,Natural Products, buy Dihydrocorynantheine , Dihydrocorynantheine supplier , purchase Dihydrocorynantheine , Dihydrocorynantheine cost , Dihydrocorynantheine manufacturer , order Dihydrocorynantheine , high purity Dihydrocorynantheine

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: