EpicurzerenoneCAS# 20085-85-2 |
- Curzerenone
Catalog No.:BCN3009
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Quality Control & MSDS
3D structure
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Number of papers citing our products
| Cas No. | 20085-85-2 | SDF | Download SDF |
| PubChem ID | 5317062 | Appearance | Powder |
| Formula | C15H18O2 | M.Wt | 230.3 |
| Type of Compound | Sesquiterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (5R,6S)-6-ethenyl-3,6-dimethyl-5-prop-1-en-2-yl-5,7-dihydro-1-benzofuran-4-one | ||
| SMILES | CC1=COC2=C1C(=O)C(C(C2)(C)C=C)C(=C)C | ||
| Standard InChIKey | ZVMJXSJCBLRAPD-DZGCQCFKSA-N | ||
| Standard InChI | InChI=1S/C15H18O2/c1-6-15(5)7-11-12(10(4)8-17-11)14(16)13(15)9(2)3/h6,8,13H,1-2,7H2,3-5H3/t13-,15+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Epicurzerenone , germacrone, curdione and curzerenone can be used as chemical markers for discrimination and quality control among different groups of samples. |
Epicurzerenone Dilution Calculator
Epicurzerenone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 4.3422 mL | 21.7108 mL | 43.4216 mL | 86.8432 mL | 108.5541 mL |
| 5 mM | 0.8684 mL | 4.3422 mL | 8.6843 mL | 17.3686 mL | 21.7108 mL |
| 10 mM | 0.4342 mL | 2.1711 mL | 4.3422 mL | 8.6843 mL | 10.8554 mL |
| 50 mM | 0.0868 mL | 0.4342 mL | 0.8684 mL | 1.7369 mL | 2.1711 mL |
| 100 mM | 0.0434 mL | 0.2171 mL | 0.4342 mL | 0.8684 mL | 1.0855 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Antimicrobial activity and cytotoxicity of the essential oil of Curcuma zedoaria.[Pubmed:15315265]
Am J Chin Med. 2004;32(2):281-90.
The chemical compositions of the essential oil of Curcuma zedoaria (Berg.) Rosc. were analyzed by gas chromatography-mass spectrometry (GC-MS) and showed a high content of Epicurzerenone and curdione representing 46.6% and 13.7% of the total oil, respectively. The essential oil was evaluated for potential antimicrobial activity against Staphylococcus aureus, Escherichia coli, Pseudomonasa aeruginosa, Vibrio parahaemolyticus, Salmonella typhimurium and Bacillus cereus. V. parahaemolyticus was sensitive to the presence of the essential oil, while the most resistant strain appeared to be E. coli. Based on 3-(4,5-dimethylthiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide (MTT) assay, nitroblue tetrazolium (NBT) reduction and cell morphology, the essential oil of C. zedoaria could inhibit the proliferation of human promyelocytic leukemia HL-60 cells. These results suggest that the essential oil has the antimicrobial activity against some of Gram- positive and negative pathogenic microorganisms and the components of the extract lead to the apoptosis of human cancer cell line.
Metabolomics study on quality control and discrimination of three curcuma species based on gas chromatograph-mass spectrometry.[Pubmed:21433157]
Phytochem Anal. 2011 Sep-Oct;22(5):411-8.
INTRODUCTION: Metabonomic analysis is an important molecular phenotyping method for characterising plant ecotypic variations; hence, it may become a powerful tool for quality control and discrimination of traditional Chinese medicine (TCM). OBJECTIVE: To discriminate and assess the quality of Curcuma phaeocaulis, C. kwangsiensis and C. wenyujin from different ecotypes. The identification of the compositions of essential oils from the three Curcuma species was included in this study. METHODOLOGY: Metabolomics analysis was carried out on all samples by gas chromatography-mass spectrometry (GC-MS) coupled with multivariate statistical analysis. Characterisation of phytochemicals in essential oils was performed by automated matching to the MS library and comparison of their mass spectra (NIST05 database). RESULTS: Principal component analysis (PCA) effectively distinguished the samples from different species and ecotypes. Partial least squares discrimination analysis (PLS-DA) was successfully employed in classifying the GC-MS data of authentic, commercial and introduction cultivation samples. Furthermore, the components contributing significantly to the discrimination, namely curzerenone, germacrone, curdione and Epicurzerenone, were screened by PCA and PLS-DA loading plots and further can be used as chemical markers for discrimination and quality control among different groups of samples.
