Pseudoneolinderane

CAS# 20082-45-5

Pseudoneolinderane

2D Structure

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Quality Control of Pseudoneolinderane

3D structure

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Pseudoneolinderane

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Chemical Properties of Pseudoneolinderane

Cas No. 20082-45-5 SDF Download SDF
PubChem ID 497202 Appearance Powder
Formula C15H16O4 M.Wt 260.29
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,8R,10S)-3,8-dimethyl-5,9,15-trioxatetracyclo[11.2.1.02,6.08,10]hexadeca-2(6),3,13(16)-trien-14-one
SMILES CC1=COC2=C1C3C=C(CCC4C(C2)(O4)C)C(=O)O3
Standard InChIKey NJMLHRWYACXVHJ-IFUGULHKSA-N
Standard InChI InChI=1S/C15H16O4/c1-8-7-17-11-6-15(2)12(19-15)4-3-9-5-10(13(8)11)18-14(9)16/h5,7,10,12H,3-4,6H2,1-2H3/t10-,12+,15-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Pseudoneolinderane

The roots of Lindera aggregata

Protocol of Pseudoneolinderane

Structure Identification
Chinese Chemical Letters, 2002, 13(10):965-967.

A new sesquiterpene from the roots of Lindera strychnifolia.[Reference: WebLink]


METHODS AND RESULTS:
A new sesquiterpene lactone, strychnilactone (1), together with five known sesquite- rpenoids, linderane (2), lindenenol (3), linderalactone (4), hydroxylindestenolide (5), Pseudoneolinderane (6) have been isolated from the extracts of Supercritical Fluid Extraction of Lindera strychnifolia.
CONCLUSIONS:
The structure of the new compound was elucidated by means of spectroscopic analysis. And the relative configuration of 1 was assigned on the basis of NOE analysis.

Pseudoneolinderane Dilution Calculator

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Pseudoneolinderane Molarity Calculator

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Preparing Stock Solutions of Pseudoneolinderane

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.8419 mL 19.2093 mL 38.4187 mL 76.8374 mL 96.0467 mL
5 mM 0.7684 mL 3.8419 mL 7.6837 mL 15.3675 mL 19.2093 mL
10 mM 0.3842 mL 1.9209 mL 3.8419 mL 7.6837 mL 9.6047 mL
50 mM 0.0768 mL 0.3842 mL 0.7684 mL 1.5367 mL 1.9209 mL
100 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7684 mL 0.9605 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Pseudoneolinderane

Anti-inflammatory furanogermacrane sesquiterpenes from Neolitsea parvigemma.[Pubmed:15702642]

Nat Prod Res. 2005 Apr;19(3):283-6.

Six furanogermacrane sesquiterpenes, Pseudoneolinderane (1), linderalactone (2), zeylanidine (3), zeylanicine (4), deacetylzeylanidine (5), and neolitrane (6), isolated from the stems of Neolitsea parvigemma, were tested for anti-inflammatory activities. Among them, 1 and 2 showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB. The IC50 of 1 and 2 were found to be 3.21 and 8.48 microg/mL, respectively.

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