EpistephamiersineCAS# 52389-15-8 |
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Chemical structure
3D structure
Cas No. | 52389-15-8 | SDF | Download SDF |
PubChem ID | 91895297 | Appearance | Powder |
Formula | C21H27NO6 | M.Wt | 389.5 |
Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
Chemical Name | (1S,8S,10S,11R,12S)-3,4,11,12-tetramethoxy-17-methyl-18-oxa-17-azapentacyclo[8.4.3.18,11.01,10.02,7]octadeca-2(7),3,5-trien-13-one | ||
SMILES | CN1CCC23C14CC(C5=C2C(=C(C=C5)OC)OC)OC4(C(C(=O)C3)OC)OC | ||
Standard InChIKey | UTTZNWQGZHNUIG-JMMIECQRSA-N | ||
Standard InChI | InChI=1S/C21H27NO6/c1-22-9-8-19-10-13(23)18(26-4)21(27-5)20(19,22)11-15(28-21)12-6-7-14(24-2)17(25-3)16(12)19/h6-7,15,18H,8-11H2,1-5H3/t15-,18-,19-,20-,21-/m0/s1 | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | Standard reference |
Structure Identification | Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(15):1973-7.Hasubanan type alkaloids in Stephania hernandifolia.[Pubmed: 20931849]
To study the hasubanan type alkaloids in Stephania hernandifolia.
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Epistephamiersine Dilution Calculator
Epistephamiersine Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 2.5674 mL | 12.837 mL | 25.6739 mL | 51.3479 mL | 64.1849 mL |
5 mM | 0.5135 mL | 2.5674 mL | 5.1348 mL | 10.2696 mL | 12.837 mL |
10 mM | 0.2567 mL | 1.2837 mL | 2.5674 mL | 5.1348 mL | 6.4185 mL |
50 mM | 0.0513 mL | 0.2567 mL | 0.5135 mL | 1.027 mL | 1.2837 mL |
100 mM | 0.0257 mL | 0.1284 mL | 0.2567 mL | 0.5135 mL | 0.6418 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
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[Hasubanan type alkaloids in Stephania hernandifolia].[Pubmed:20931849]
Zhongguo Zhong Yao Za Zhi. 2010 Aug;35(15):1973-7.
OBJECTIVE: To study the hasubanan type alkaloids in Stephania hernandifolia. METHOD: The dried herbs of S. hernandifolia. were extracted with 95% ethanol. After removal of the solvent, the residue was first partitioned between acid water and petroleum ether, then the aqueous layer was basified and extracted with chloroform to obtain crude alkaloids. Column chromatograghic methods with on silica gel, Rp-18, MCI CHP 20P, Sephadex LH-20 were applied for the isolation and purification of the crude alkaloid fraction. The structures were elucidated by their physicochemical properties and spectral data. RESULT: Nine hasubanan type alkaloids were obtained and identified as aknadinine(1), longanone(2), stephasunoline (3), N-methylstephuline(4), Epistephamiersine(5), prostephabyssine(6), aknadilactam(7), dihydroEpistephamiersine(8), hasubanonine(9). CONCLUSION: Compounds 2-8 were isolated from this plant for the first time.