GSK 789472 hydrochlorideD3 antagonist. Also D2 partial agonist CAS# 1257326-24-1 |
Related Products
- Bromodomain Inhibitor, (+)-JQ1
Catalog No.:BCC1132
CAS No.:1268524-70-4
- (-)-JQ1
Catalog No.:BCC3603
CAS No.:1268524-71-5
- MS436
Catalog No.:BCC4037
CAS No.:1395084-25-9
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 1257326-24-1 | SDF | Download SDF |
PubChem ID | 57347570 | Appearance | Powder |
Formula | C15H22ClN3O | M.Wt | 295.81 |
Type of Compound | N/A | Storage | Desiccate at -20°C |
Solubility | Soluble to 100 mM in water and to 100 mM in DMSO | ||
Chemical Name | 1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one;hydrochloride | ||
SMILES | C1CCNC(C1)CN2CCN(C2=O)C3=CC=CC=C3.Cl | ||
Standard InChIKey | BYJUVPWUMBVSTK-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C15H21N3O.ClH/c19-15-17(12-13-6-4-5-9-16-13)10-11-18(15)14-7-2-1-3-8-14;/h1-3,7-8,13,16H,4-6,9-12H2;1H | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | Selective dopamine D3 receptor antagonist and D2 partial agonist (pEC50 values are <5.5 and 8.3 respectively). Selective against the D4 receptor in both agonist and antagonist assays. Brain penetrant. |
GSK 789472 hydrochloride Dilution Calculator
GSK 789472 hydrochloride Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 3.3805 mL | 16.9027 mL | 33.8055 mL | 67.611 mL | 84.5137 mL |
5 mM | 0.6761 mL | 3.3805 mL | 6.7611 mL | 13.5222 mL | 16.9027 mL |
10 mM | 0.3381 mL | 1.6903 mL | 3.3805 mL | 6.7611 mL | 8.4514 mL |
50 mM | 0.0676 mL | 0.3381 mL | 0.6761 mL | 1.3522 mL | 1.6903 mL |
100 mM | 0.0338 mL | 0.169 mL | 0.3381 mL | 0.6761 mL | 0.8451 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- NPEC-caged-dopamine
Catalog No.:BCC7837
CAS No.:1257326-23-0
- NPEC-caged-serotonin
Catalog No.:BCC7836
CAS No.:1257326-22-9
- NPEC-caged-(S)-3,4-DCPG
Catalog No.:BCC7652
CAS No.:1257323-85-5
- NPEC-caged-(S)-AMPA
Catalog No.:BCC7789
CAS No.:1257323-84-4
- NPEC-caged-noradrenalin
Catalog No.:BCC7835
CAS No.:1257323-83-3
- TC-G 24
Catalog No.:BCC6146
CAS No.:1257256-44-2
- TC-SP 14
Catalog No.:BCC7926
CAS No.:1257093-40-5
- ABT-199
Catalog No.:BCC3614
CAS No.:1257044-40-8
- TPTU
Catalog No.:BCC2827
CAS No.:125700-71-2
- TDBTU
Catalog No.:BCC2825
CAS No.:125700-69-8
- TBTU
Catalog No.:BCC2823
CAS No.:125700-67-6
- (-)-Epicatechin gallate
Catalog No.:BCN6327
CAS No.:1257-08-5
New Products
- TC-E 5006
Catalog No.:BCC7981
CAS No.:1257395-14-4
- TBA354
Catalog No.:BCC6459
CAS No.:1257426-19-9
- Amikacin hydrate
Catalog No.:BCC4621
CAS No.:1257517-67-1
- CEP-33779
Catalog No.:BCC2199
CAS No.:1257704-57-6
- Pristimerin
Catalog No.:BCN2315
CAS No.:1258-84-0
- Parathyroid Hormone (1-34), bovine
Catalog No.:BCC1040
CAS No.:12583-68-5
- Deacetylorientalide
Catalog No.:BCN7310
CAS No.:1258517-59-7
- 9-O-Ethyldeacetylorientalide
Catalog No.:BCN7311
CAS No.:1258517-60-0
- LY2940680
Catalog No.:BCC3935
CAS No.:1258861-20-9
- (+)-Glaucarubinone
Catalog No.:BCN7956
CAS No.:1259-86-5
- 24-Methylenecycloartanol acetate
Catalog No.:BCN6137
CAS No.:1259-94-5
- SAMS Peptide
Catalog No.:BCC5745
CAS No.:125911-68-4
The identification of a selective dopamine D2 partial agonist, D3 antagonist displaying high levels of brain exposure.[Pubmed:20153647]
Bioorg Med Chem Lett. 2010 Mar 15;20(6):2013-6.
The identification of a highly selective D(2) partial agonist, D(3) antagonist tool molecule which demonstrates high levels of brain exposure and selectivity against an extensive range of dopamine, serotonin, adrenergic, histamine, and muscarinic receptors is described.
GSK 789472 hydrochloride,1257326-24-1,Natural Products,Dopamine Receptor, buy GSK 789472 hydrochloride , GSK 789472 hydrochloride supplier , purchase GSK 789472 hydrochloride , GSK 789472 hydrochloride cost , GSK 789472 hydrochloride manufacturer , order GSK 789472 hydrochloride , high purity GSK 789472 hydrochloride