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GSK256066 2,2,2-trifluoroacetic acid

PDE4 inhibitor CAS# 1415560-64-3

GSK256066 2,2,2-trifluoroacetic acid

Catalog No. BCC1605----Order now to get a substantial discount!

Product Name & Size Price Stock
GSK256066 2,2,2-trifluoroacetic acid: 5mg $138 In Stock
GSK256066 2,2,2-trifluoroacetic acid: 10mg Please Inquire In Stock
GSK256066 2,2,2-trifluoroacetic acid: 20mg Please Inquire Please Inquire
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GSK256066 2,2,2-trifluoroacetic acid: 500mg Please Inquire Please Inquire
GSK256066 2,2,2-trifluoroacetic acid: 1000mg Please Inquire Please Inquire
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Quality Control of GSK256066 2,2,2-trifluoroacetic acid

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Chemical structure

GSK256066 2,2,2-trifluoroacetic acid

3D structure

Chemical Properties of GSK256066 2,2,2-trifluoroacetic acid

Cas No. 1415560-64-3 SDF Download SDF
PubChem ID 71576691 Appearance Powder
Formula C29H27F3N4O7S M.Wt 632.61
Type of Compound N/A Storage Desiccate at -20°C
Solubility DMSO : 50 mg/mL (79.04 mM; Need ultrasonic)
Chemical Name 6-[3-(dimethylcarbamoyl)phenyl]sulfonyl-4-(3-methoxyanilino)-8-methylquinoline-3-carboxamide;2,2,2-trifluoroacetic acid
SMILES CC1=C2C(=CC(=C1)S(=O)(=O)C3=CC=CC(=C3)C(=O)N(C)C)C(=C(C=N2)C(=O)N)NC4=CC(=CC=C4)OC.C(=O)(C(F)(F)F)O
Standard InChIKey PTTKEASHQDSBJR-UHFFFAOYSA-N
Standard InChI InChI=1S/C27H26N4O5S.C2HF3O2/c1-16-11-21(37(34,35)20-10-5-7-17(12-20)27(33)31(2)3)14-22-24(16)29-15-23(26(28)32)25(22)30-18-8-6-9-19(13-18)36-4;3-2(4,5)1(6)7/h5-15H,1-4H3,(H2,28,32)(H,29,30);(H,6,7)
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

GSK256066 2,2,2-trifluoroacetic acid Dilution Calculator

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GSK256066 2,2,2-trifluoroacetic acid Molarity Calculator

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Preparing Stock Solutions of GSK256066 2,2,2-trifluoroacetic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5808 mL 7.9038 mL 15.8075 mL 31.6151 mL 39.5188 mL
5 mM 0.3162 mL 1.5808 mL 3.1615 mL 6.323 mL 7.9038 mL
10 mM 0.1581 mL 0.7904 mL 1.5808 mL 3.1615 mL 3.9519 mL
50 mM 0.0316 mL 0.1581 mL 0.3162 mL 0.6323 mL 0.7904 mL
100 mM 0.0158 mL 0.079 mL 0.1581 mL 0.3162 mL 0.3952 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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Background on GSK256066 2,2,2-trifluoroacetic acid

GSK256066(GSK-256066) is an exceptionally high affinity and selective PDE4 inhibitor with an IC50 of 3.2 pM for PDE4B.

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Description

GSK 256066 Trifluoroacetate (GSK256066 2,2,2-trifluoroacetic acid) is a selective and high-affinity phosphodiesterase 4 (PDE) inhibitor, with an IC50 of 3.2 pM for PDE4B; developed for the treatment of chronic obstructive pulmonary disease.

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