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Ginsenoside Rd2

CAS# 83480-64-2

Ginsenoside Rd2

Catalog No. BCN8279----Order now to get a substantial discount!

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Chemical structure

Ginsenoside Rd2

3D structure

Chemical Properties of Ginsenoside Rd2

Cas No. 83480-64-2 SDF Download SDF
PubChem ID 21672569 Appearance White powder
Formula C47H80O17 M.Wt 917.13
Type of Compound N/A Storage Desiccate at -20°C
Synonyms Quinquenoside L10
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5S)-3,4,5-trihydroxyoxan-2-yl]oxymethyl]oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxane-3,4,5-triol
SMILES CC(=CCCC(C)(C1CCC2(C1C(CC3C2(CCC4C3(CCC(C4(C)C)OC5C(C(C(C(O5)CO)O)O)O)C)C)O)C)OC6C(C(C(C(O6)COC7C(C(C(CO7)O)O)O)O)O)O)C
Standard InChIKey ZTQSADJAYQOCDD-FDDSVCGKSA-N
Standard InChI InChI=1S/C47H80O17/c1-22(2)10-9-14-47(8,64-42-39(58)36(55)34(53)27(62-42)21-60-40-37(56)32(51)25(50)20-59-40)23-11-16-46(7)31(23)24(49)18-29-44(5)15-13-30(43(3,4)28(44)12-17-45(29,46)6)63-41-38(57)35(54)33(52)26(19-48)61-41/h10,23-42,48-58H,9,11-21H2,1-8H3/t23-,24+,25-,26+,27+,28-,29+,30-,31-,32-,33+,34+,35-,36-,37+,38+,39+,40-,41-,42-,44-,45+,46+,47-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Ginsenoside Rd2

The roots of Panax ginseng C. A. Mey.

Ginsenoside Rd2 Dilution Calculator

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Ginsenoside Rd2 Molarity Calculator

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Preparing Stock Solutions of Ginsenoside Rd2

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0904 mL 5.4518 mL 10.9036 mL 21.8072 mL 27.2589 mL
5 mM 0.2181 mL 1.0904 mL 2.1807 mL 4.3614 mL 5.4518 mL
10 mM 0.109 mL 0.5452 mL 1.0904 mL 2.1807 mL 2.7259 mL
50 mM 0.0218 mL 0.109 mL 0.2181 mL 0.4361 mL 0.5452 mL
100 mM 0.0109 mL 0.0545 mL 0.109 mL 0.2181 mL 0.2726 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ginsenoside Rd2

Comparative study on chemical components and anti-inflammatory effects of Panax notoginseng flower extracted by water and methanol.[Pubmed:29068139]

J Sep Sci. 2017 Dec;40(24):4730-4739.

Methanol and water are commonly used solvents for chemical analysis and traditional decoction, respectively. In the present study, a high-performance liquid chromatography with ultraviolet detection method was developed to quantify 11 saponins in Panax notoginseng flower extracted by aqueous solution and methanol, and chemical components and anti-inflammatory effects of these two extracts were compared. The separation of 11 saponins, including notoginsenoside Fc and ginsenoside Rc, was well achieved on a Zorbax SB C18 column. This developed method provides an adequate linearity (r(2) > 0.999), repeatability (RSD < 4.26%), inter- and intraday variations (RSD < 3.20%) with recovery (94.7-104.1%) of 11 saponins concerned. Our data indicated that ginsenoside biotransformation in PNF was found, when water was used as the extraction solvent, but not methanol. Specifically, the major components of Panax notoginseng flower, ginsenosides Rb1, Rc, Rb2, Rb3, and Rd, can be near completely transformed to the minor components, gypenoside XVII, notoginsenoside Fe, Ginsenoside Rd2, notoginsenoside Fd, and ginsenoside F2, respectively. Total protein isolated from Panax notoginseng flower is responsible for this ginsenoside biotransformation. Additionally, methanol extract exerted the stronger anti-inflammatory effects than water extract in lipopolysaccharide-induced RAW264.7 cells. This difference in anti-inflammatory action might be attributed to their chemical difference of saponins.

[Chemical constituents of leaves of Panax japonicus var. major].[Pubmed:25095375]

Zhongguo Zhong Yao Za Zhi. 2014 May;39(9):1635-8.

Seven compounds were isolated from the leaves of Panax japonicus var. major by chromatographic methods including silica gel, Sephadex LH-20, ODS and semi-preparative HPLC. Their structures were elucidated by their physical and chemical properties and spectral data analysis as 5, 7-dihydroxy-8-methoxyl flavone (1), ginsenoside Rs2 (2), quinquenoside R1 (3), ginsenoside Rs1 (4), notoginsenoside Fe (5), Ginsenoside Rd2 (6) and gypenosiden IX (7). Among them, compound 1 was obtained from the Panax genus for the first time, and compounds 2-7 were isolated from this plant for the first time.

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