Isocolumbin

CAS# 471-54-5

Isocolumbin

Catalog No. BCN5361----Order now to get a substantial discount!

Product Name & Size Price Stock
Isocolumbin: 5mg Please Inquire In Stock
Isocolumbin: 10mg Please Inquire In Stock
Isocolumbin: 20mg Please Inquire Please Inquire
Isocolumbin: 50mg Please Inquire Please Inquire
Isocolumbin: 100mg Please Inquire Please Inquire
Isocolumbin: 200mg Please Inquire Please Inquire
Isocolumbin: 500mg Please Inquire Please Inquire
Isocolumbin: 1000mg Please Inquire Please Inquire
Related Products
  • Columbin

    Catalog No.:BCN2622
    CAS No.:546-97-4

Quality Control of Isocolumbin

Number of papers citing our products

Chemical structure

Isocolumbin

3D structure

Chemical Properties of Isocolumbin

Cas No. 471-54-5 SDF Download SDF
PubChem ID 24721165 Appearance Powder
Formula C20H22O6 M.Wt 358.39
Type of Compound Diterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1S,2S,3S,5S,8S,11R,12S)-5-(furan-3-yl)-12-hydroxy-3,11-dimethyl-6,14-dioxatetracyclo[10.2.2.02,11.03,8]hexadec-15-ene-7,13-dione
SMILES CC12CCC3C(=O)OC(CC3(C1C4C=CC2(C(=O)O4)O)C)C5=COC=C5
Standard InChIKey AALLCALQGXXWNA-UKFLMKJWSA-N
Standard InChI InChI=1S/C20H22O6/c1-18-9-14(11-5-8-24-10-11)25-16(21)12(18)3-6-19(2)15(18)13-4-7-20(19,23)17(22)26-13/h4-5,7-8,10,12-15,23H,3,6,9H2,1-2H3/t12-,13+,14+,15+,18-,19-,20-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Isocolumbin

The roots of Stephania tetrandra S.Moore

Biological Activity of Isocolumbin

Description1. Isocolumbin has significant anti-inflammatory activity. 2. Isocolumbin has antimicrobial activity.
TargetsAntifection | Immunology & Inflammation related

Isocolumbin Dilution Calculator

Concentration (start)
x
Volume (start)
=
Concentration (final)
x
Volume (final)
 
 
 
C1
V1
C2
V2

calculate

Isocolumbin Molarity Calculator

Mass
=
Concentration
x
Volume
x
MW*
 
 
 
g/mol

calculate

Preparing Stock Solutions of Isocolumbin

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.7903 mL 13.9513 mL 27.9026 mL 55.8051 mL 69.7564 mL
5 mM 0.5581 mL 2.7903 mL 5.5805 mL 11.161 mL 13.9513 mL
10 mM 0.279 mL 1.3951 mL 2.7903 mL 5.5805 mL 6.9756 mL
50 mM 0.0558 mL 0.279 mL 0.5581 mL 1.1161 mL 1.3951 mL
100 mM 0.0279 mL 0.1395 mL 0.279 mL 0.5581 mL 0.6976 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Organizitions Citing Our Products recently

 
 
 

Calcutta University

University of Minnesota

University of Maryland School of Medicine

University of Illinois at Chicago

The Ohio State University

University of Zurich

Harvard University

Colorado State University

Auburn University

Yale University

Worcester Polytechnic Institute

Washington State University

Stanford University

University of Leipzig

Universidade da Beira Interior

The Institute of Cancer Research

Heidelberg University

University of Amsterdam

University of Auckland
TsingHua University
TsingHua University
The University of Michigan
The University of Michigan
Miami University
Miami University
DRURY University
DRURY University
Jilin University
Jilin University
Fudan University
Fudan University
Wuhan University
Wuhan University
Sun Yat-sen University
Sun Yat-sen University
Universite de Paris
Universite de Paris
Deemed University
Deemed University
Auckland University
Auckland University
The University of Tokyo
The University of Tokyo
Korea University
Korea University
Featured Products
New Products
 

References on Isocolumbin

Anti-inflammatory activities of the methanol extracts and an isolated furanoditerpene constituent of Sphenocentrum jollyanum Pierre (Menispermaceae).[Pubmed:16236477]

J Ethnopharmacol. 2006 Mar 8;104(1-2):87-91.

Sphenocentrum jollyanum crude extracts and an isolated constituent were evaluated for anti-inflammatory activity using the carrageenan-induced hind paw oedema of healthy adult albino rats and utilizing the oral route of administration. The fruit methanol extract (79.58% inhibition at 200 mg kg(-1)) gave a higher anti-inflammatory activity than the root extract (53.75% inhibition at 200 mg ml(-1)). Further purification of the most active fruit methanol extract (MFE) led to the isolation of three furanoditerpenes identified as columbin, Isocolumbin, fibleucin (uv, ir, nmr and ms) as well as a flavonoid-rich fraction (FDE). Both columbin (67.08% inhibition at 20 mg kg(-1), p<0.05) and FDE (76.25% inhibition at 200 mg kg(-1); p<0.05) gave significant anti-inflammatory activities in comparable range with reference acetylsalicylic acid (72.5% inhibition at 100 mg kg(-1)). The results provide some justification for the folkloric uses of Sphenocentrum jollyanum in the treatment of inflammatory-based diseases across the West African sub-region.

Description

Isocolumbin is a diterpenoid isolated from Jateorhiza palmate Miers (Colombo root).

Keywords:

Isocolumbin,471-54-5,Natural Products, buy Isocolumbin , Isocolumbin supplier , purchase Isocolumbin , Isocolumbin cost , Isocolumbin manufacturer , order Isocolumbin , high purity Isocolumbin

Online Inquiry for:

      Fill out the information below

      • Size:Qty: - +

      * Required Fields

                                      Result: