Jolkinolide ECAS# 54494-34-7 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 54494-34-7 | SDF | Download SDF |
| PubChem ID | 5318716 | Appearance | Cryst. |
| Formula | C20H28O2 | M.Wt | 300.4 |
| Type of Compound | Diterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (4aR,10aR,11aR,11bR)-4,4,8,11b-tetramethyl-2,3,4a,5,6,10a,11,11a-octahydro-1H-naphtho[2,1-f][1]benzofuran-9-one | ||
| SMILES | CC1=C2C=C3CCC4C(CCCC4(C3CC2OC1=O)C)(C)C | ||
| Standard InChIKey | ZXEVPUOHSXARBR-VIPLHTEESA-N | ||
| Standard InChI | InChI=1S/C20H28O2/c1-12-14-10-13-6-7-17-19(2,3)8-5-9-20(17,4)15(13)11-16(14)22-18(12)21/h10,15-17H,5-9,11H2,1-4H3/t15-,16-,17-,20+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Standard reference |
| Structure Identification | Zhong Yao Cai. 2009 Sep;32(9):1390-2.Studies on the chemical constituents from Euphorbia chrysocoma.[Pubmed: 20034213]To study the chemical constituents from the aerial part of Euphorbia chrysocoma.
Zhongguo Zhong Yao Za Zhi. 1995 Mar;20(3):169-71, 192.Chemical constituents of Euphorbia nematocypha Hand.-Mazz.[Pubmed: 7646781]
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Jolkinolide E Dilution Calculator
Jolkinolide E Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.3289 mL | 16.6445 mL | 33.2889 mL | 66.5779 mL | 83.2224 mL |
| 5 mM | 0.6658 mL | 3.3289 mL | 6.6578 mL | 13.3156 mL | 16.6445 mL |
| 10 mM | 0.3329 mL | 1.6644 mL | 3.3289 mL | 6.6578 mL | 8.3222 mL |
| 50 mM | 0.0666 mL | 0.3329 mL | 0.6658 mL | 1.3316 mL | 1.6644 mL |
| 100 mM | 0.0333 mL | 0.1664 mL | 0.3329 mL | 0.6658 mL | 0.8322 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Chemical constituents of Euphorbia nematocypha Hand.-Mazz].[Pubmed:7646781]
Zhongguo Zhong Yao Za Zhi. 1995 Mar;20(3):169-71, 192.
Four compounds were isolated from the roots of Euphorbia nematocypha. Three of them were identified as A'-neogammacer-22(29)-en-3 beta-ol (18 beta.21 alpha) (II), Jolkinolide E (III) and beta-sitoesterol (IV). Among them, II was obtained from the genus Euphorbia and III from this plant for the first time.
[Studies on the chemical constituents from Euphorbia chrysocoma].[Pubmed:20034213]
Zhong Yao Cai. 2009 Sep;32(9):1390-2.
OBJECTIVE: To study the chemical constituents from the aerial part of Euphorbia chrysocoma. METHODS: All compounds were isolated and purified by many methods, including siliga gel and reversed phase RP-18 column chromatographies, preparative thin layer chromatography, Sephadex LH-20, and recrystallization. Their structures were mainly elucidated by ESI-MS and NMR spectra and their physical characters. RESULTS: Six compounds were isolated from the petroleum ether section from 75% ethanol extraction of the material. Their structures were identified as taraxerol (1), epitaraxerol (2), beta-sistosterol (3), beta-sitostenone (4), Jolkinolide E (5), and sesamin (6). CONCLUSION: Compounds 1, 2, 4, 5, and 6 are isolated from this plant for the first time.
