LY-411575 isomer 1CAS# 209984-58-7 |
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Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 209984-58-7 | SDF | Download SDF |
| PubChem ID | 78357869 | Appearance | Powder |
| Formula | C26H23F2N3O4 | M.Wt | 479.48 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | Soluble in DMSO | ||
| Chemical Name | (2S)-2-[[(2R)-2-(3,5-difluorophenyl)-2-hydroxyacetyl]amino]-N-[(7S)-5-methyl-6-oxo-7H-benzo[d][1]benzazepin-7-yl]propanamide | ||
| SMILES | CC(C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)C(C4=CC(=CC(=C4)F)F)O | ||
| Standard InChIKey | ULSSJYNJIZWPSB-AETJINEWSA-N | ||
| Standard InChI | InChI=1S/C26H23F2N3O4/c1-14(29-25(34)23(32)15-11-16(27)13-17(28)12-15)24(33)30-22-20-9-4-3-7-18(20)19-8-5-6-10-21(19)31(2)26(22)35/h3-14,22-23,32H,1-2H3,(H,29,34)(H,30,33)/t14-,22-,23+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
LY-411575 isomer 1 Dilution Calculator
LY-411575 isomer 1 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0856 mL | 10.428 mL | 20.8559 mL | 41.7119 mL | 52.1398 mL |
| 5 mM | 0.4171 mL | 2.0856 mL | 4.1712 mL | 8.3424 mL | 10.428 mL |
| 10 mM | 0.2086 mL | 1.0428 mL | 2.0856 mL | 4.1712 mL | 5.214 mL |
| 50 mM | 0.0417 mL | 0.2086 mL | 0.4171 mL | 0.8342 mL | 1.0428 mL |
| 100 mM | 0.0209 mL | 0.1043 mL | 0.2086 mL | 0.4171 mL | 0.5214 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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LY-411575 isomer 1 is an isomer of LY411575, which is a potent γ-secretase inhibitor.
References:
[1]. Fauq AH, et al. A multigram chemical synthesis of the gamma-secretase inhibitor LY411575 and its diastereoisomers. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6392-5. Epub 2007 Aug 30.
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LY-411575 isomer 1 is an isomer of LY411575, which is a potent γ-secretase inhibitor.
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