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Ligurobustoside N

CAS# 583058-07-5

Ligurobustoside N

Catalog No. BCN0965----Order now to get a substantial discount!

Product Name & Size Price Stock
Ligurobustoside N: 5mg Please Inquire In Stock
Ligurobustoside N: 10mg Please Inquire In Stock
Ligurobustoside N: 20mg Please Inquire Please Inquire
Ligurobustoside N: 50mg Please Inquire Please Inquire
Ligurobustoside N: 100mg Please Inquire Please Inquire
Ligurobustoside N: 200mg Please Inquire Please Inquire
Ligurobustoside N: 500mg Please Inquire Please Inquire
Ligurobustoside N: 1000mg Please Inquire Please Inquire

Quality Control of Ligurobustoside N

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Chemical structure

Ligurobustoside N

3D structure

Chemical Properties of Ligurobustoside N

Cas No. 583058-07-5 SDF Download SDF
PubChem ID 10350139 Appearance Powder
Formula C35H46O18 M.Wt 754.7
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name [(2R,3R,4R,5R,6R)-4-[(2S,3R,4S,5R,6S)-3,4-dihydroxy-6-methyl-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(hydroxymethyl)-6-[2-(4-hydroxyphenyl)ethoxy]oxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
SMILES CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(C(OC(C3OC(=O)C=CC4=CC(=C(C=C4)O)O)CO)OCCC5=CC=C(C=C5)O)O)C)O)O)O
Standard InChIKey SQXKPAMOLXJEEU-FVCUGLHDSA-N
Standard InChI InChI=1S/C35H46O18/c1-15-24(41)25(42)27(44)34(48-15)52-30-16(2)49-35(28(45)26(30)43)53-32-29(46)33(47-12-11-17-3-7-19(37)8-4-17)50-22(14-36)31(32)51-23(40)10-6-18-5-9-20(38)21(39)13-18/h3-10,13,15-16,22,24-39,41-46H,11-12,14H2,1-2H3/b10-6+/t15-,16-,22+,24-,25+,26-,27+,28+,29+,30-,31+,32+,33+,34-,35-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Ligurobustoside N Dilution Calculator

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Ligurobustoside N Molarity Calculator

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Preparing Stock Solutions of Ligurobustoside N

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.325 mL 6.6251 mL 13.2503 mL 26.5006 mL 33.1257 mL
5 mM 0.265 mL 1.325 mL 2.6501 mL 5.3001 mL 6.6251 mL
10 mM 0.1325 mL 0.6625 mL 1.325 mL 2.6501 mL 3.3126 mL
50 mM 0.0265 mL 0.1325 mL 0.265 mL 0.53 mL 0.6625 mL
100 mM 0.0133 mL 0.0663 mL 0.1325 mL 0.265 mL 0.3313 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Ligurobustoside N

Activity of Ligustrum robustum (Roxb.) Blume extract against the biofilm formation and exopolysaccharide synthesis of Streptococcus mutans.[Pubmed:33316854]

Mol Oral Microbiol. 2021 Feb;36(1):67-79.

Ligustrum robustum (Roxb.) Blume is utilized as a traditional Chinese herbal tea with various health benefits and protective effects. Streptococcus mutans is an important cariogenic oral bacteria species. The present study aimed to assess the influence of Ligustrum robustum extract (LRE) on the biofilm formation of S. mutans and the mechanism of its action, as well as to identify its chemical components. For chemical identification, HPLC-MS and nuclear magnetic resonance were applied and four identified phytochemicals were reported (Ligurobustoside B, Ligurobustoside N, Ligurobustoside J, and Ligurobustoside C). The dose-dependent (0.5 to 2.0 mug/muL) antimicrobial toxicity of LRE against S. mutans biofilm formation and exopolysaccharide (EPS) synthesis was evaluated by confocal laser scanning microscopy (CLSM), Crystal violet stain, and CFU counting. The microstructure of S. mutans biofilm treated with LRE was investigated both on glass coverslips and ex vivo bovine dental enamel by scanning electron microscopy (SEM). Moreover, LRE downregulated the expression of S. mutans glucosyltransferase-encoding genes gtfB, gtfC, and gtfD, and the quorum sensing (QS) factors comD and comE, suggesting its toxic mechanism. In addition, the result of CCK-8 test on human oral cells revealed an acceptable biocompatibility of LRE. These findings indicated the possible application of this daily consumed herbal tea for caries prevention.

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