MaackiaflavanoneCAS# 156162-10-6 |
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| Cas No. | 156162-10-6 | SDF | Download SDF |
| PubChem ID | 124355910 | Appearance | Powder |
| Formula | C26H30O6 | M.Wt | 438.51 |
| Type of Compound | Flavonoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2S)-2-[2,4-dihydroxy-5-(3-methylbut-2-enyl)phenyl]-5-hydroxy-7-methoxy-8-(3-methylbut-2-enyl)-2,3-dihydrochromen-4-one | ||
| SMILES | CC(=CCC1=C(C=C(C(=C1)C2CC(=O)C3=C(O2)C(=C(C=C3O)OC)CC=C(C)C)O)O)C | ||
| Standard InChIKey | DVNXMSLAHMVXOH-DEOSSOPVSA-N | ||
| Standard InChI | InChI=1S/C26H30O6/c1-14(2)6-8-16-10-18(20(28)11-19(16)27)24-13-22(30)25-21(29)12-23(31-5)17(26(25)32-24)9-7-15(3)4/h6-7,10-12,24,27-29H,8-9,13H2,1-5H3/t24-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The stem bark of Maackia amurensis.
| Description | 1. Maackiaflavanone B shows cytotoxic activity with IC(50) value of 7.8 microM against human cancer cell line A375S2. |
Maackiaflavanone Dilution Calculator
Maackiaflavanone Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.2804 mL | 11.4022 mL | 22.8045 mL | 45.609 mL | 57.0112 mL |
| 5 mM | 0.4561 mL | 2.2804 mL | 4.5609 mL | 9.1218 mL | 11.4022 mL |
| 10 mM | 0.228 mL | 1.1402 mL | 2.2804 mL | 4.5609 mL | 5.7011 mL |
| 50 mM | 0.0456 mL | 0.228 mL | 0.4561 mL | 0.9122 mL | 1.1402 mL |
| 100 mM | 0.0228 mL | 0.114 mL | 0.228 mL | 0.4561 mL | 0.5701 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Cytotoxic prenylated flavonoids from the stem bark of Maackia amurensis.[Pubmed:19252325]
Chem Pharm Bull (Tokyo). 2009 Mar;57(3):302-6.
Five new prenylated flavonoids, Maackiaflavanone A (1), Maackiaflavanone B (2), maackiapentone (3), maackiapterocarpan A (4), maackiapterocarpan B (5) along with eleven known flavonoids were isolated from the stem bark of Maackia amurensis. The structures of the new compounds were elucidated by spectroscopic methods. The cytotoxicities of compounds 1-4, 6, 8-12 and 14-16 against four human cancer cell lines, A375S2, HeLa, MCF-7 and HepG2, were tested by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. Among the compounds tested, compound 2 showed the strongest cytotoxic activity with IC(50) value of 7.8 microM against A375S2 and euchrenone b(1) showed the most potent cytotoxicity with IC(50) value of 4.5 microM against HeLa.
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