Methyl cis-11-eicosenoateCAS# 2390-09-2 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
| Cas No. | 2390-09-2 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C21H40O2 | M.Wt | 324.55 |
| Type of Compound | Aliphatics | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
Methyl cis-11-eicosenoate Dilution Calculator
Methyl cis-11-eicosenoate Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 3.0812 mL | 15.4059 mL | 30.8119 mL | 61.6238 mL | 77.0297 mL |
| 5 mM | 0.6162 mL | 3.0812 mL | 6.1624 mL | 12.3248 mL | 15.4059 mL |
| 10 mM | 0.3081 mL | 1.5406 mL | 3.0812 mL | 6.1624 mL | 7.703 mL |
| 50 mM | 0.0616 mL | 0.3081 mL | 0.6162 mL | 1.2325 mL | 1.5406 mL |
| 100 mM | 0.0308 mL | 0.1541 mL | 0.3081 mL | 0.6162 mL | 0.7703 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Stigmastanol
Catalog No.:BCX1450
CAS No.:83-45-4
- 16,17-Didehydroganoderic acid D
Catalog No.:BCX1449
CAS No.:1427189-02-3
- 4-Deoxyphorbol
Catalog No.:BCX1448
CAS No.:79083-67-3
- Neotame
Catalog No.:BCX1447
CAS No.:165450-17-9
- 6-Carboxyl-7-hydroxy-2,3-dimethylchromone
Catalog No.:BCX1446
CAS No.:108170-57-6
- 1β-Methoxydiversifolin
Catalog No.:BCX1445
CAS No.:110382-36-0
- Nicotinamide riboside
Catalog No.:BCX1444
CAS No.:1341-23-7
- Vernoflexuoside
Catalog No.:BCX1443
CAS No.:57576-33-7
- Rubrofusarin triglucoside
Catalog No.:BCX1442
CAS No.:245724-07-6
- Tagitinin C
Catalog No.:BCX1441
CAS No.:59979-56-5
- 3'-Hydroxyflavanone
Catalog No.:BCX1440
CAS No.:92496-65-6
- D-mannuronic acid sodium salt
Catalog No.:BCX1439
CAS No.:921-56-2
- 2'-Acetyltaxol
Catalog No.:BCX1452
CAS No.:92950-40-8
- Liraglutide
Catalog No.:BCX1453
CAS No.:204656-20-2
- Linustatin
Catalog No.:BCX1454
CAS No.:72229-40-4
- Cirsiumaldehyde
Catalog No.:BCX1455
CAS No.:7389-38-0
- Fosinopril EP impurity D
Catalog No.:BCX1456
CAS No.:1356353-41-7
- Teprenone
Catalog No.:BCX1457
CAS No.:6809-52-5
- 6α-(2-methybutyryloxy)-Britannilactone
Catalog No.:BCX1458
CAS No.:1260151-65-2
- Puerarin-4'-O-β-D-glucopyranoside
Catalog No.:BCX1459
CAS No.:117047-08-2
- 6α-isobutyryloxy-Britannilactone
Catalog No.:BCX1460
CAS No.:1259933-02-2
- 6α-isovaleryloxy-Britannilactone
Catalog No.:BCX1461
CAS No.:1259933-04-4
- 6α-(3-methylvaleryloxy)-Britannilactone
Catalog No.:BCX1462
CAS No.:1260151-66-3
- Demethylwedelolactone sulfate
Catalog No.:BCX1463
CAS No.:1318240-80-0
Metabolomic Profiling of the Immune Stimulatory Effect of Eicosenoids on PMA-Differentiated THP-1 Cells.[Pubmed:31600945]
Vaccines (Basel). 2019 Oct 9;7(4):142.
Honey bee venom has been established to have significant effect in immunotherapy. In the present study, (Z)-11-eicosenol-a major constituent of bee venom, along with its derivations Methyl cis-11-eicosenoate and cis-11-eicosenoic acid, were synthesised to investigate their immune stimulatory effect and possible use as vaccine adjuvants. Stimuli that prime and activate the immune system have exerted profound effects on immune cells, particularly macrophages; however, the effectiveness of bee venom constituents as immune stimulants has not yet been established. Here, the abilities of these compounds to act as pro-inflammatory stimuli were assessed, either alone or in combination with lipopolysaccharide (LPS), by examining the secretion of tumour necrosis factor-alpha (TNF-alpha) and the cytokines interleukin-1beta (IL-1beta), IL-6 and IL-10 by THP-1 macrophages. The compounds clearly increased the levels of IL-1beta and decreased IL-10, whereas a decrease in IL-6 levels suggested a complex mechanism of action. A more in-depth profile of macrophage behaviour was therefore obtained by comprehensive untargeted metabolic profiling of the cells using liquid chromatography mass spectrometry (LC-MS) to confirm the ability of the eicosanoids to trigger the immune system. The level of 358 polar and 315 non-polar metabolites were changed significantly (p < 0.05) by all treatments. The LPS-stimulated production of most of the inflammatory metabolite biomarkers in glycolysis, the tricarboxylic acid (TCA) cycle, the pentose phosphate pathway, purine, pyrimidine and fatty acids metabolism were significantly enhanced by all three compounds, and particularly by Methyl cis-11-eicosenoate and cis-11-eicosenoic acid. These findings support the proposed actions of (Z)-11-eicosenol, Methyl cis-11-eicosenoate and cis-11-eicosenoic acid as immune system stimulators.
