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N,N'-Bis(salicylidene)ethylenediamine

CAS# 94-93-9

N,N'-Bis(salicylidene)ethylenediamine

Catalog No. BCC9064----Order now to get a substantial discount!

Product Name & Size Price Stock
N,N'-Bis(salicylidene)ethylenediamine: 5mg $17 In Stock
N,N'-Bis(salicylidene)ethylenediamine: 10mg Please Inquire In Stock
N,N'-Bis(salicylidene)ethylenediamine: 20mg Please Inquire Please Inquire
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N,N'-Bis(salicylidene)ethylenediamine: 100mg Please Inquire Please Inquire
N,N'-Bis(salicylidene)ethylenediamine: 200mg Please Inquire Please Inquire
N,N'-Bis(salicylidene)ethylenediamine: 500mg Please Inquire Please Inquire
N,N'-Bis(salicylidene)ethylenediamine: 1000mg Please Inquire Please Inquire

Quality Control of N,N'-Bis(salicylidene)ethylenediamine

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Chemical structure

N,N'-Bis(salicylidene)ethylenediamine

3D structure

Chemical Properties of N,N'-Bis(salicylidene)ethylenediamine

Cas No. 94-93-9 SDF Download SDF
PubChem ID 5379013 Appearance Powder
Formula C16H16N2O2 M.Wt 268.3
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (6Z)-6-[[2-[[(Z)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]ethylamino]methylidene]cyclohexa-2,4-dien-1-one
SMILES C1=CC(=CNCCNC=C2C=CC=CC2=O)C(=O)C=C1
Standard InChIKey RQHVNNWVDLRULK-XSYHWHKQSA-N
Standard InChI InChI=1S/C16H16N2O2/c19-15-7-3-1-5-13(15)11-17-9-10-18-12-14-6-2-4-8-16(14)20/h1-8,11-12,17-18H,9-10H2/b13-11-,14-12-
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

N,N'-Bis(salicylidene)ethylenediamine Dilution Calculator

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N,N'-Bis(salicylidene)ethylenediamine Molarity Calculator

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Preparing Stock Solutions of N,N'-Bis(salicylidene)ethylenediamine

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.7272 mL 18.6359 mL 37.2717 mL 74.5434 mL 93.1793 mL
5 mM 0.7454 mL 3.7272 mL 7.4543 mL 14.9087 mL 18.6359 mL
10 mM 0.3727 mL 1.8636 mL 3.7272 mL 7.4543 mL 9.3179 mL
50 mM 0.0745 mL 0.3727 mL 0.7454 mL 1.4909 mL 1.8636 mL
100 mM 0.0373 mL 0.1864 mL 0.3727 mL 0.7454 mL 0.9318 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on N,N'-Bis(salicylidene)ethylenediamine

Treatment of oral cancer using magnetized paclitaxel.[Pubmed:29643995]

Oncotarget. 2018 Feb 26;9(21):15591-15605.

N,N'-Bis(salicylidene)ethylenediamine iron (Fe(Salen)) is an anti-cancer agent with intrinsic magnetic property. Here, we covalently linked Fe(Salen) to paclitaxel (PTX), a widely used anti-cancer drug, to obtain a magnetized paclitaxel conjugate (M-PTX), which exhibited magnetic characteristics for magnet-guided drug delivery and MRI visualization. M-PTX increased apoptosis and G2/M arrest of cultured human oral cancer cell lines in the same manner as PTX. Furthermore, marked contrast intensity was obtained in magnetic resonance imaging (MRI) of M-PTX. In a mouse oral cancer model, a permanent magnet placed on the body surface adjacent to the tumor resulted in distinct accumulation of M-PTX, and the anti-cancer effect was greater than that of M-PTX without the magnet. We believe that this strategy may improve future cancer chemotherapy by providing conventional anti-cancer drugs with novel functionalities such as magnet-guided drug delivery or MRI-based visualization/quantitation of drug distribution.

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