NVP-QAV-572CAS# 957209-68-6 |
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Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 957209-68-6 | SDF | Download SDF |
| PubChem ID | 23581840 | Appearance | Powder |
| Formula | C17H19F2N7O3S2 | M.Wt | 471.5 |
| Type of Compound | N/A | Storage | Desiccate at -20°C |
| Solubility | DMSO : 125 mg/mL (265.11 mM; Need ultrasonic) | ||
| Chemical Name | 1-[2-[2-(2-fluoroethyl)tetrazol-5-yl]ethyl]-3-[5-(3-fluoro-4-methylsulfonylphenyl)-4-methyl-1,3-thiazol-2-yl]urea | ||
| SMILES | CC1=C(SC(=N1)NC(=O)NCCC2=NN(N=N2)CCF)C3=CC(=C(C=C3)S(=O)(=O)C)F | ||
| Standard InChIKey | UGEZRRNNFHAJTM-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C17H19F2N7O3S2/c1-10-15(11-3-4-13(12(19)9-11)31(2,28)29)30-17(21-10)22-16(27)20-7-5-14-23-25-26(24-14)8-6-18/h3-4,9H,5-8H2,1-2H3,(H2,20,21,22,27) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | NVP-QAV-572 is a PI3K inhibitor extracted from patent US7998990B2, Compound Example 8, has an IC50 of 10 nM.In Vitro:NVP-QAV-572 (Example 8) is useful in the treatment of conditions which are mediated by the activation of the Pi3 kinase enzymes, particularly inflammatory or allergic conditions[1]. References: | |||||
NVP-QAV-572 Dilution Calculator
NVP-QAV-572 Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.1209 mL | 10.6045 mL | 21.2089 mL | 42.4178 mL | 53.0223 mL |
| 5 mM | 0.4242 mL | 2.1209 mL | 4.2418 mL | 8.4836 mL | 10.6045 mL |
| 10 mM | 0.2121 mL | 1.0604 mL | 2.1209 mL | 4.2418 mL | 5.3022 mL |
| 50 mM | 0.0424 mL | 0.2121 mL | 0.4242 mL | 0.8484 mL | 1.0604 mL |
| 100 mM | 0.0212 mL | 0.106 mL | 0.2121 mL | 0.4242 mL | 0.5302 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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NVP-QAV-572 is a potent PI3K kianse inhibitor with IC50 of 10 nM.
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NVP-QAV-572 is a PI3K inhibitor extracted from patent US7998990B2, Compound Example 8, has an IC50 of 10 nM.
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