Nefopam HClCAS# 23327-57-3 |
- Dexmedetomidine HCl
Catalog No.:BCC4347
CAS No.:145108-58-3
- Xylazine HCl
Catalog No.:BCC4341
CAS No.:23076-35-9
- Guanfacine
Catalog No.:BCC5180
CAS No.:29110-47-2
- Sotalol
Catalog No.:BCC4356
CAS No.:3930-20-9
- Isoprenaline HCl
Catalog No.:BCC4328
CAS No.:51-30-9
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
Cas No. | 23327-57-3 | SDF | Download SDF |
PubChem ID | 155290 | Appearance | Powder |
Formula | C17H20ClNO | M.Wt | 289.8 |
Type of Compound | N/A | Storage | Desiccate at -20°C |
Synonyms | Fenazoxine hydrochloride | ||
Solubility | H2O : 14 mg/mL (48.31 mM; Need ultrasonic and warming); | ||
Chemical Name | 5-methyl-1-phenyl-1,3,4,6-tetrahydro-2,5-benzoxazocine;hydrochloride | ||
SMILES | [H+].[Cl-].CN1CCOC(c2ccccc2)c3ccccc3C1 | ||
Standard InChIKey | CNNVSINJDJNHQK-UHFFFAOYSA-N | ||
Standard InChI | InChI=1S/C17H19NO.ClH/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18;/h2-10,17H,11-13H2,1H3;1H | ||
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. |
Description | Nefopam is a centrally-acting but non-opioid analgesic drug, for the relief of moderate to severe pain. |
Nefopam HCl Dilution Calculator
Nefopam HCl Molarity Calculator
1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
1 mM | 3.4507 mL | 17.2533 mL | 34.5066 mL | 69.0131 mL | 86.2664 mL |
5 mM | 0.6901 mL | 3.4507 mL | 6.9013 mL | 13.8026 mL | 17.2533 mL |
10 mM | 0.3451 mL | 1.7253 mL | 3.4507 mL | 6.9013 mL | 8.6266 mL |
50 mM | 0.069 mL | 0.3451 mL | 0.6901 mL | 1.3803 mL | 1.7253 mL |
100 mM | 0.0345 mL | 0.1725 mL | 0.3451 mL | 0.6901 mL | 0.8627 mL |
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. |
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Nefopam HCl is an centrally-acting but non-opioid analgesic drug by blocking voltage-gated sodium channel and inhibition of serotonin, dopamine and noradrenaline reuptake.
- Cephalexin monohydrate
Catalog No.:BCC4096
CAS No.:23325-78-2
- Emodin-8-beta-D-glucoside
Catalog No.:BCN6329
CAS No.:23313-21-5
- Delta 7-avenasterol
Catalog No.:BCN3212
CAS No.:23290-26-8
- Probucol
Catalog No.:BCC4833
CAS No.:23288-49-5
- m-NH2-Tyr-OH.2HCl
Catalog No.:BCC3340
CAS No.:23279-22-3
- VAL-083
Catalog No.:BCC2024
CAS No.:23261-20-3
- Bay 36-7620
Catalog No.:BCC5915
CAS No.:232605-26-4
- 4'-O-Methylvitexin
Catalog No.:BCN2642
CAS No.:2326-34-3
- Guanabenz Acetate
Catalog No.:BCC4327
CAS No.:23256-50-0
- Dimaprit dihydrochloride
Catalog No.:BCC6672
CAS No.:23256-33-9
- Riddelline
Catalog No.:BCN2133
CAS No.:23246-96-0
- 5,7-Diacetoxy-8-methoxyflavone
Catalog No.:BCN5083
CAS No.:23246-80-2
- MK 0343
Catalog No.:BCC6170
CAS No.:233275-76-8
- Glycoborinine
Catalog No.:BCN7462
CAS No.:233279-39-5
- L-Ser(Bzl)-ol
Catalog No.:BCC2579
CAS No.:23356-96-9
- Vinleurosine
Catalog No.:BCN2608
CAS No.:23360-92-1
- (1S,2R)-2-Amino-1,2-diphenylethanol
Catalog No.:BCC8385
CAS No.:23364-44-5
- Theviridoside
Catalog No.:BCN5084
CAS No.:23407-76-3
- Phalaenopsine T
Catalog No.:BCN2014
CAS No.:23412-97-7
- Phalaenopsine La
Catalog No.:BCN2015
CAS No.:23412-99-9
- 7-Isopentenyloxy-gamma-fagarine
Catalog No.:BCN5085
CAS No.:23417-92-7
- Tetrahydropiperin
Catalog No.:BCN6708
CAS No.:23434-88-0
- Swertianolin
Catalog No.:BCN2759
CAS No.:23445-00-3
- Irisolidone
Catalog No.:BCN8496
CAS No.:2345-17-7
Nefopam HCl interaction study with eight other drugs.[Pubmed:16799]
J Int Med Res. 1976;4(3):195-201.
A controlled clinical trial was undertaken to determine potential for drug interaction of Nefopam HCl, a new analgesic, with eight other widely used compounds. Nefopam HCl was administered in combination with these drugs and placebo to forty-five healthy volunteer subjects in nine groups of five subjects each. Possible drug interactions were detected by the occurrence of side-effects and interference with bioavailability of the new analgesic, also by changes in vital signs or in various laboratory tests. Results indicated no statistically significant differences in these parameters between the Nefopam HCl-placebo regimen and the other eight combinations. Despite this, there were substantial clinical differences in the intensity and incidence of side-effects with combinations of codeine, pentazocine and propoxyphene. These differences warrant further study. Serum Nefopam HCl levels were significantly higher on Day 3 than on Day 1, indicating no defect in bioavailability due to drug interaction. Overall, results of this study support the feasibility of concomitant use of these eight drugs with Nefopam HCl for short treatment periods.