Perforatumone

CAS# 827319-50-6

Perforatumone

2D Structure

Catalog No. BCN4370----Order now to get a substantial discount!

Product Name & Size Price Stock
Perforatumone: 5mg Please Inquire In Stock
Perforatumone: 10mg Please Inquire In Stock
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Quality Control of Perforatumone

3D structure

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Perforatumone

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Chemical Properties of Perforatumone

Cas No. 827319-50-6 SDF Download SDF
PubChem ID 91885221 Appearance Powder
Formula C35H52O5 M.Wt 552.8
Type of Compound Miscellaneous Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,3S,4R,5R,6S)-4-methyl-1,3,6-tris(3-methylbut-2-enyl)-5-(3-methyl-2-oxobutanoyl)-4-(4-methylpent-3-enyl)-7-oxabicyclo[4.2.1]nonane-8,9-dione
SMILES CC(C)C(=O)C(=O)C1C(C(CC2(C(=O)C1(OC2=O)CC=C(C)C)CC=C(C)C)CC=C(C)C)(C)CCC=C(C)C
Standard InChIKey MDEFUUIAPRQDDQ-AWJYBGKTSA-N
Standard InChI InChI=1S/C35H52O5/c1-22(2)13-12-18-33(11)27(15-14-23(3)4)21-34(19-16-24(5)6)31(38)35(40-32(34)39,20-17-25(7)8)30(33)29(37)28(36)26(9)10/h13-14,16-17,26-27,30H,12,15,18-21H2,1-11H3/t27-,30+,33+,34+,35-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Perforatumone

The herbs of Hypericum henryi

Biological Activity of Perforatumone

Description1. Perforatumone may exhibit inhibitory activities against acetylcholinesterase and human tumor cell lines.
TargetsAChR

Perforatumone Dilution Calculator

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Perforatumone Molarity Calculator

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Preparing Stock Solutions of Perforatumone

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.809 mL 9.0449 mL 18.0897 mL 36.1795 mL 45.2243 mL
5 mM 0.3618 mL 1.809 mL 3.6179 mL 7.2359 mL 9.0449 mL
10 mM 0.1809 mL 0.9045 mL 1.809 mL 3.6179 mL 4.5224 mL
50 mM 0.0362 mL 0.1809 mL 0.3618 mL 0.7236 mL 0.9045 mL
100 mM 0.0181 mL 0.0904 mL 0.1809 mL 0.3618 mL 0.4522 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Perforatumone

Polycyclic Polyprenylated Acylphloroglucinol Congeners Possessing Diverse Structures from Hypericum henryi.[Pubmed:25871261]

J Nat Prod. 2015 Apr 24;78(4):885-95.

Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of hybrid natural products sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways and showing considerable structural and bioactive diversity. In a systematic phytochemical investigation of Hypericum henryi, 40 PPAP-type derivatives, including the new compounds hyphenrones G-Q, were obtained. These compounds represent 12 different structural types, including four unusual skeletons exemplified by 5, 8, 10, and 17. The 12 different core structures found are explicable in terms of their biosynthetic origin. The structure of a known PPAP, Perforatumone, was revised to hyphenrone A (5) by NMR spectroscopic and biomimetic synthesis methods. Several compounds exhibited inhibitory activities against acetylcholinesterase and human tumor cell lines. This study deals with the structural diversity, function, and biogenesis of natural PPAPs.

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