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(-)-Pinoresinol 4-O-glucoside

CAS# 41607-20-9

(-)-Pinoresinol 4-O-glucoside

2D Structure

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3D structure

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(-)-Pinoresinol 4-O-glucoside

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Chemical Properties of (-)-Pinoresinol 4-O-glucoside

Cas No. 41607-20-9 SDF Download SDF
PubChem ID 11168362 Appearance Powder
Formula C26H32O11 M.Wt 520.53
Type of Compound Lignans Storage Desiccate at -20°C
Synonyms 24404-49-7;Epipinoresinol-4-O-beta-D-glucoside
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (2S,3R,4S,5S,6R)-2-[4-[(3R,3aS,6R,6aS)-3-(4-hydroxy-3-methoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]-2-methoxyphenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol
SMILES COC1=C(C=CC(=C1)C2C3COC(C3CO2)C4=CC(=C(C=C4)OC5C(C(C(C(O5)CO)O)O)O)OC)O
Standard InChIKey QLJNETOQFQXTLI-JKUDBEEXSA-N
Standard InChI InChI=1S/C26H32O11/c1-32-18-7-12(3-5-16(18)28)24-14-10-35-25(15(14)11-34-24)13-4-6-17(19(8-13)33-2)36-26-23(31)22(30)21(29)20(9-27)37-26/h3-8,14-15,20-31H,9-11H2,1-2H3/t14-,15-,20-,21-,22+,23-,24+,25+,26-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of (-)-Pinoresinol 4-O-glucoside

The caulis of Lonicera japonica THUNB and/or the rhizomes of Polygonatum sibiricum Red.

Biological Activity of (-)-Pinoresinol 4-O-glucoside

Description(-)-Pinoresinol 4-O-glucoside is a natural product from Lonicera japonica THUNB.

Protocol of (-)-Pinoresinol 4-O-glucoside

Structure Identification
Natural Product Sciences, 2010, 16(1):15-19.

Ligeaes from Lonicerae caulis.[Reference: WebLink]


METHODS AND RESULTS:
A new 2,7'-cyclolignan named lonicerinol (1) along with eight known lignans, (-)-epipinoresinol (2), (-)-pinoresinol (3), 9alpha-hydroxypinoresinol (4), 7R,8S-dihydrodehydrodiconiferyl alcohol (5), (+-)-neo-olivil (6), (+)-isolaricireshiol (7), 3-methoxy-8,4'-oxyneoligna-3',4,7,9,9'-pentol (8), and (-)-Pinoresinol 4-O-glucoside (9), were isolated from the caulis of Lonicera japonica THUNB. (Caprifoliaceae). All of these constituents except for (-)-pinoresinol (3) and 9alpha-hydroxypinoresinol (4) are reported for the first time from the genus Lonicera.
CONCLUSIONS:
The structures and absolute configurations of these compounds were determined on the basis of spectroscopic analysis, including CD and 1D- and 2D-NMR techniques and chemical methods.

(-)-Pinoresinol 4-O-glucoside Dilution Calculator

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(-)-Pinoresinol 4-O-glucoside Molarity Calculator

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Preparing Stock Solutions of (-)-Pinoresinol 4-O-glucoside

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.9211 mL 9.6056 mL 19.2112 mL 38.4224 mL 48.028 mL
5 mM 0.3842 mL 1.9211 mL 3.8422 mL 7.6845 mL 9.6056 mL
10 mM 0.1921 mL 0.9606 mL 1.9211 mL 3.8422 mL 4.8028 mL
50 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7684 mL 0.9606 mL
100 mM 0.0192 mL 0.0961 mL 0.1921 mL 0.3842 mL 0.4803 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on (-)-Pinoresinol 4-O-glucoside

Ligeaes from Lonicerae caulis

Natural product sciences,2010,16(1):15-19.

A new 2,7'-cyclolignan named lonicerinol (1) along with eight known lignans, (-)-epipinoresinol (2), (-)-pinoresinol (3), 9alpha-hydroxypinoresinol (4), 7R,8S-dihydrodehydrodiconiferyl alcohol (5), (+-)-neo-olivil (6), (+)-isolaricireshiol (7), 3-methoxy-8,4'-oxyneoligna-3',4,7,9,9'-pentol (8), and (-)-Pinoresinol 4-O-glucoside (9), were isolated from the caulis of Lonicera japonica THUNB. (Caprifoliaceae). All of these constituents except for (-)-pinoresinol (3) and 9alpha-hydroxypinoresinol (4) are reported for the first time from the genus Lonicera. The structures and absolute configurations of these compounds were determined on the basis of spectroscopic analysis, including CD and 1D- and 2D-NMR techniques and chemical methods.

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