Poricoic acid GCAS# 415724-84-4 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 415724-84-4 | SDF | Download SDF |
| PubChem ID | 5471966 | Appearance | Powder |
| Formula | C30H46O5 | M.Wt | 486.7 |
| Type of Compound | Triterpenoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R)-2-[(2R,3R,3aR,6S,7S,9bR)-6-(2-carboxyethyl)-2-hydroxy-3a,6,9b-trimethyl-7-prop-1-en-2-yl-1,2,3,4,5,7,8,9-octahydrocyclopenta[a]naphthalen-3-yl]-6-methylhept-5-enoic acid | ||
| SMILES | CC(=CCCC(C1C(CC2(C1(CCC3=C2CCC(C3(C)CCC(=O)O)C(=C)C)C)C)O)C(=O)O)C | ||
| Standard InChIKey | VPTZOSBKEDUOFE-KXGBKNTBSA-N | ||
| Standard InChI | InChI=1S/C30H46O5/c1-18(2)9-8-10-20(27(34)35)26-24(31)17-30(7)23-12-11-21(19(3)4)28(5,15-14-25(32)33)22(23)13-16-29(26,30)6/h9,20-21,24,26,31H,3,8,10-17H2,1-2,4-7H3,(H,32,33)(H,34,35)/t20-,21+,24-,26+,28+,29-,30+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The roots of Wolfiporia cocos (Schw.) Ryv.
| Description | 1. Poricoic acid G shows inhibition of tumor-promoting effects and cytotoxic activity. |
Poricoic acid G Dilution Calculator
Poricoic acid G Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0547 mL | 10.2733 mL | 20.5465 mL | 41.0931 mL | 51.3663 mL |
| 5 mM | 0.4109 mL | 2.0547 mL | 4.1093 mL | 8.2186 mL | 10.2733 mL |
| 10 mM | 0.2055 mL | 1.0273 mL | 2.0547 mL | 4.1093 mL | 5.1366 mL |
| 50 mM | 0.0411 mL | 0.2055 mL | 0.4109 mL | 0.8219 mL | 1.0273 mL |
| 100 mM | 0.0205 mL | 0.1027 mL | 0.2055 mL | 0.4109 mL | 0.5137 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- RI-1
Catalog No.:BCC1896
CAS No.:415713-60-9
- SN-6
Catalog No.:BCC7273
CAS No.:415697-08-4
- N6-Cyclopentyladenosine
Catalog No.:BCC7160
CAS No.:41552-82-3
- 1-(3,4-dimethoxyphenyl)-2-(4-allly-2,6-dimethoxyphenoxy)propan-1-ol
Catalog No.:BCN1445
CAS No.:41535-95-9
- 2,6,16-Kauranetriol
Catalog No.:BCN5472
CAS No.:41530-90-9
- Koaburaside monomethyl ether
Catalog No.:BCN5471
CAS No.:41514-64-1
- Daturaolone
Catalog No.:BCN3904
CAS No.:41498-80-0
- 12-Oleanene-3,6-diol
Catalog No.:BCN3903
CAS No.:41498-79-7
- 3-Amino-1-phenyl-2-pyrazolin-5-one
Catalog No.:BCC8605
CAS No.:4149-06-8
- Belinostat (PXD101)
Catalog No.:BCC2153
CAS No.:414864-00-9
- Turkesterone
Catalog No.:BCN2363
CAS No.:41451-87-0
- Bruceantin
Catalog No.:BCN7618
CAS No.:41451-75-6
New Products
- Carboplatin
Catalog No.:BCC1170
CAS No.:41575-94-4
- 4,R-ajmalicine N-oxide
Catalog No.:BCN5473
CAS No.:41590-29-8
- (-)-Pinoresinol 4-O-glucoside
Catalog No.:BCN7251
CAS No.:41607-20-9
- Ylangenol
Catalog No.:BCN6705
CAS No.:41610-69-9
- Ciclopirox ethanolamine
Catalog No.:BCC4372
CAS No.:41621-49-2
- Lacinilene C
Catalog No.:BCN5474
CAS No.:41653-72-9
- Koaburaside
Catalog No.:BCN5475
CAS No.:41653-73-0
- 7-O-Methyl morroniside
Catalog No.:BCN3882
CAS No.:41679-97-4
- Catharanthine hemitartrate
Catalog No.:BCN8463
CAS No.:4168-17-6
- 2H-1-Benzopyran-7-yloxy
Catalog No.:BCN3580
CAS No.:41680-08-4
- 4',7-Dihydroxyflavanone
Catalog No.:BCC8333
CAS No.:41680-09-5
- 8-Methyleugenitol
Catalog No.:BCN6459
CAS No.:41682-21-7
Inhibition of tumor-promoting effects by poricoic acids G and H and other lanostane-type triterpenes and cytotoxic activity of poricoic acids A and G from Poria cocos.[Pubmed:11975480]
J Nat Prod. 2002 Apr;65(4):462-5.
The structures of two novel 3,4-seco-lanostane-type triterpenes isolated from the sclerotium of Poria cocos were established to be 16alpha-hydroxy-3,4-seco-lanosta-4(28),8,24-triene-3,21-dioic acid (1; Poricoic acid G) and 16alpha-hydroxy-3,4-seco-24-methyllanosta-4(28),8,24(24(1))-triene-3,21-dioic acid (2; poricoic acid H) on the basis of spectroscopic methods. These two, and eight other known compounds isolated from the sclerotium, poricoic acid B (3), poricoic acid A (4), tumulosic acid (5), dehydrotumulosic acid (6), 3-epidehydrotumulosic acid (7), polyporenic acid C (8), 25-hydroxy-3-epidehydrotumulosic acid (9), and dehydroabietic acid methyl ester (10), showed potent inhibitory effects on Epstein-Barr virus early antigen (EBV-EA) activation induced by the tumor promoter 12-O-tetradecanoylphorbol-13-acetate (TPA). Evaluation of the cytotoxicity of compounds 1 and 4 against human cancer cell lines revealed that 1 was significantly cytotoxic to leukemia HL-60 cells [GI(50) (concentration that yields 50% growth) value 39.3 nM], although it showed only moderate cytotoxicity to the other cells. Compound 4 exhibited moderate cytotoxicity to all of the cancer cell lines tested.
Poricoic acid G,415724-84-4,Natural Products, buy Poricoic acid G , Poricoic acid G supplier , purchase Poricoic acid G , Poricoic acid G cost , Poricoic acid G manufacturer , order Poricoic acid G , high purity Poricoic acid G
