PregomisinCAS# 66280-26-0 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 66280-26-0 | SDF | Download SDF |
| PubChem ID | 181796 | Appearance | Oil |
| Formula | C22H30O6 | M.Wt | 390.47 |
| Type of Compound | Lignans | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 5-[(2S,3R)-4-(3-hydroxy-4,5-dimethoxyphenyl)-2,3-dimethylbutyl]-2,3-dimethoxyphenol | ||
| SMILES | CC(CC1=CC(=C(C(=C1)OC)OC)O)C(C)CC2=CC(=C(C(=C2)OC)OC)O | ||
| Standard InChIKey | RLRKIWSBYUZHIJ-OKILXGFUSA-N | ||
| Standard InChI | InChI=1S/C22H30O6/c1-13(7-15-9-17(23)21(27-5)19(11-15)25-3)14(2)8-16-10-18(24)22(28-6)20(12-16)26-4/h9-14,23-24H,7-8H2,1-6H3/t13-,14+ | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Pregomisin shows platelet-activating factor (PAF) antagonistic activity and the IC 50 value is 4.8x10(-5) M. |
| Targets | PAFR |
| In vitro | Platelet-activating factor antagonistic activity and(13)C NMR assignment of pregomisin and chamigrenal fromSchisandra chinensis.[Pubmed: 18982271]Arch Pharm Res. 1997 Dec;20(6):633-6.
|
| Structure Identification | Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1281-3.Lignans from Schisandra propinqua var. propinqua.[Pubmed: 17666862]
|
Pregomisin Dilution Calculator
Pregomisin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.561 mL | 12.8051 mL | 25.6102 mL | 51.2203 mL | 64.0254 mL |
| 5 mM | 0.5122 mL | 2.561 mL | 5.122 mL | 10.2441 mL | 12.8051 mL |
| 10 mM | 0.2561 mL | 1.2805 mL | 2.561 mL | 5.122 mL | 6.4025 mL |
| 50 mM | 0.0512 mL | 0.2561 mL | 0.5122 mL | 1.0244 mL | 1.2805 mL |
| 100 mM | 0.0256 mL | 0.1281 mL | 0.2561 mL | 0.5122 mL | 0.6403 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Gomisin J
Catalog No.:BCN2270
CAS No.:66280-25-9
- 4-Amino-2-methylquinoline
Catalog No.:BCC8677
CAS No.:6628-04-2
- 6'-O-Acetylpaniculoside II
Catalog No.:BCC8316
CAS No.:
- Stemonidine
Catalog No.:BCC8253
CAS No.:66267-46-7
- N-dotriacontanol
Catalog No.:BCC8218
CAS No.:6624-79-9
- N-Benzylanthranilic acid
Catalog No.:BCC9093
CAS No.:6622-55-5
- Cyromazine
Catalog No.:BCC5328
CAS No.:66215-27-8
- Deacetylxylopic acid
Catalog No.:BCN4210
CAS No.:6619-95-0
- Malic acid 4-Me ester
Catalog No.:BCN4209
CAS No.:66178-02-7
- Cimicifugoside
Catalog No.:BCN2623
CAS No.:66176-93-0
- Chromolaenide
Catalog No.:BCN7341
CAS No.:66148-25-2
- Levalbuterol tartrate
Catalog No.:BCC4217
CAS No.:661464-94-4
- 3H-1,2-Benzodithiol-3-one-1,1-dioxide
Catalog No.:BCC8633
CAS No.:66304-01-6
- ML 171
Catalog No.:BCC6252
CAS No.:6631-94-3
- Dihydroguaiaretic acid
Catalog No.:BCN4212
CAS No.:66322-34-7
- 5'-Deoxy-5-fluorocytidine
Catalog No.:BCC8746
CAS No.:66335-38-4
- Ranitidine
Catalog No.:BCC9134
CAS No.:66357-35-5
- Ranitidine Hydrochloride
Catalog No.:BCC4533
CAS No.:66357-59-3
- TGX-221
Catalog No.:BCC1244
CAS No.:663619-89-4
- Methylsyringol
Catalog No.:BCN3535
CAS No.:6638-05-7
- (+)-Apogossypol
Catalog No.:BCC5585
CAS No.:66389-74-0
- Chloranthalactone A
Catalog No.:BCN8022
CAS No.:66395-02-6
- Chloranthalactone B
Catalog No.:BCN8020
CAS No.:66395-03-7
- 5alpha-Hydroxychloranthalactone A
Catalog No.:BCN7469
CAS No.:66395-04-8
Lignans from Schisandra propinqua var. propinqua.[Pubmed:17666862]
Chem Pharm Bull (Tokyo). 2007 Aug;55(8):1281-3.
Two new dibenzocyclooctadiene lignans angeloyl-(+)-gomisin K(3) (1) and methylisogomisin O (2), together with six known ones, isogomisin O, angeloylisogomisin O, gomisin O, angeloygomisin O, benzoylgomisin O, epigomisin O, and four 1,4-bis(phenyl)-2,3-dimethylbutane type lignans, Pregomisin, meso-dihydroguaiaretic acid, isoanwulignan, and sphenanlignan were isolated from the aerial parts of Schisandra propinqua var. propinqua. The structures of 1 and 2 were elucidated by spectroscopic methods including extensive 1D- and 2D-NMR techniques.
Platelet-activating factor antagonistic activity and(13)C NMR assignment of pregomisin and chamigrenal fromSchisandra chinensis.[Pubmed:18982271]
Arch Pharm Res. 1997 Dec;20(6):633-6.
In the course of searching for PAF receptor antagonists, Pregomisin (1) and chamigrenal (2) were isolated from the fruits ofSchizandra chinensis Baill by the bioactivity-guided isolation. Both compounds showed PAF antagonistic activity and the IC(50) values were 4.8x10(-5) M and 1.2x10(-4) M, respectively. In addition, the(13)C NMR assignments of1 and2 using DEPT, HMQC, COLOC and HMBC were reported for the first time.
