Rehmannioside ACAS# 81720-05-0 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 81720-05-0 | SDF | Download SDF |
| PubChem ID | 78407230 | Appearance | Powder |
| Formula | C21H32O15 | M.Wt | 524.5 |
| Type of Compound | Iridoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 2-(hydroxymethyl)-6-[[3,4,5-trihydroxy-6-[[5-hydroxy-2-(hydroxymethyl)-3,9-dioxatricyclo[4.4.0.02,4]dec-7-en-10-yl]oxy]oxan-2-yl]methoxy]oxane-3,4,5-triol | ||
| SMILES | C1=COC(C2C1C(C3C2(O3)CO)O)OC4C(C(C(C(O4)COC5C(C(C(C(O5)CO)O)O)O)O)O)O | ||
| Standard InChIKey | DTNSOISBYQKHCS-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C21H32O15/c22-3-7-11(25)13(27)15(29)19(33-7)32-4-8-12(26)14(28)16(30)20(34-8)35-18-9-6(1-2-31-18)10(24)17-21(9,5-23)36-17/h1-2,6-20,22-30H,3-5H2 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Rehmannioside A is an iridoid glucoside. |
| In vivo | Absorption and pharmacokinetics of radix rehmanniae in rats.[Pubmed: 24358782]Yao Xue Xue Bao. 2013 Sep;48(9):1464-70.
In this paper, absorption and pharmacokinetic study of Radix Rehmanniae was studied by liquid chromatography coupled with mass spectrometry method after oral administration to rats.
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| Structure Identification | Journal of Shenyang Pharmaceutical University, 2013 , 30 (7) :506-8.Isolation and identification of the chemical constituents from Rehmannia glutinosa L.[Reference: WebLink]To study the chemical constituents from Rehmannia glutinosa. |
Rehmannioside A Dilution Calculator
Rehmannioside A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.9066 mL | 9.5329 mL | 19.0658 mL | 38.1316 mL | 47.6644 mL |
| 5 mM | 0.3813 mL | 1.9066 mL | 3.8132 mL | 7.6263 mL | 9.5329 mL |
| 10 mM | 0.1907 mL | 0.9533 mL | 1.9066 mL | 3.8132 mL | 4.7664 mL |
| 50 mM | 0.0381 mL | 0.1907 mL | 0.3813 mL | 0.7626 mL | 0.9533 mL |
| 100 mM | 0.0191 mL | 0.0953 mL | 0.1907 mL | 0.3813 mL | 0.4766 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Rehmannioside A is an iridoid glucoside.
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[Absorption and pharmacokinetics of radix rehmanniae in rats].[Pubmed:24358782]
Yao Xue Xue Bao. 2013 Sep;48(9):1464-70.
In this paper, absorption and pharmacokinetic study of Radix Rehmanniae was studied by liquid chromatography coupled with mass spectrometry method after oral administration to rats. By comparing the chromatograms of ultraviolet, full scan, extracted ion and selective reaction monitoring (SRM) of standard solution, Radix Rehmanniae, blank plasma and rat plasma post drug administration, catalpol and ajugol were found to be the main compounds absorbed from Radix Rehmanniae. Plasma concentrations of aucubin, dihydrocatalpol, Rehmannioside A (or rehmannioside B/ melittoside) and rehmannioside D were very low. Quantitative method for catalpol and aucubin and semi-quantitative method for other compounds in rat plasma were established. The pharmacokinetic study of those absorbed components was conducted after oral administration of 6 g x kg(-1) Radix Rehmanniae water extract to rats. Cmax, t(1/2) and AUC(0-infinity) of catalpol and ajugol were (2349.05 +/- 1438.34) and (104.25 +/- 82.05) ng x mL(-1), (0.86 +/- 0.32) and (0.96 +/- 0.37) h, (4407.58 +/- 2734.89) and (226.66 +/- 188.38) ng x h x mL(-1), respectively. tmax was at 1.00 h for catalpol and ajugol. Both catalpol and ajugol were absorbed and excreted rapidly.
