Salaspermic acid

CAS# 71247-78-4

Salaspermic acid

Catalog No. BCN7139----Order now to get a substantial discount!

Product Name & Size Price Stock
Salaspermic acid: 5mg $828 In Stock
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Quality Control of Salaspermic acid

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Chemical structure

Salaspermic acid

3D structure

Chemical Properties of Salaspermic acid

Cas No. 71247-78-4 SDF Download SDF
PubChem ID 44593364 Appearance Powder
Formula C30H48O4 M.Wt 472.71
Type of Compound Triterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (1R,4S,5R,8S,11R,13R,14S,17R,18S,21S,24R)-21-hydroxy-5,8,11,14,17,24-hexamethyl-22-oxahexacyclo[19.2.1.01,18.04,17.05,14.08,13]tetracosane-11-carboxylic acid
SMILES CC1C23CCC4C(C2CCC1(OC3)O)(CCC5(C4(CCC6(C5CC(CC6)(C)C(=O)O)C)C)C)C
Standard InChIKey ZXENWDWQTWYUGY-UUZWCOCASA-N
Standard InChI InChI=1S/C30H48O4/c1-19-29-9-7-20-26(4,21(29)8-10-30(19,33)34-18-29)14-16-28(6)22-17-25(3,23(31)32)12-11-24(22,2)13-15-27(20,28)5/h19-22,33H,7-18H2,1-6H3,(H,31,32)/t19-,20+,21+,22-,24-,25-,26-,27-,28+,29+,30+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Salaspermic acid

The stem barks of Kokoona ochracea.

Biological Activity of Salaspermic acid

Description1. Salaspermic acid is an inhibitor of HIV reverse transcriptase and HIV replication in H9 lymphocyte cells.
TargetsHIV

Salaspermic acid Dilution Calculator

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Salaspermic acid Molarity Calculator

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Preparing Stock Solutions of Salaspermic acid

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1155 mL 10.5773 mL 21.1546 mL 42.3092 mL 52.8865 mL
5 mM 0.4231 mL 2.1155 mL 4.2309 mL 8.4618 mL 10.5773 mL
10 mM 0.2115 mL 1.0577 mL 2.1155 mL 4.2309 mL 5.2887 mL
50 mM 0.0423 mL 0.2115 mL 0.4231 mL 0.8462 mL 1.0577 mL
100 mM 0.0212 mL 0.1058 mL 0.2115 mL 0.4231 mL 0.5289 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Salaspermic acid

[Studies on triterpenoids of total glucosides of tripterygium wilfordii].[Pubmed:7720147]

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1994 Dec;16(6):466-8.

Three more triterpenoids were isolated from total glucosides of tripterygium wilfordii (T1). T16 and T17 were identified as Salaspermic acid and as wilforlide B. T18 was a new compound. The structure of T18 was determined, as 3-oxo-22 alpha-hydroxy-delta 12-oleanen-29-oic acid by detail spectroscopic and chemical analysis, and named triptotriterpenonic acid A.

Quinone-methide triterpenes and salaspermic acid from Kokoona ochracea.[Pubmed:8158155]

J Nat Prod. 1994 Jan;57(1):1-8.

Tingenone[1],20-hydroxy-20-epi-tingenone[2],celastrol[ 3], and Salaspermic acid [4] have been isolated from Kokoona ochracea stem bark. The quinone-methide triterpenes 1-3 exhibited strong but non-specific in vitro cytotoxicity against P-388 murine lymphocytic leukemia cells and a panel of human cancer cell lines. Salaspermic acid [4] was not active in all the cancer cell lines used in this investigation. 13C-nmr spectra assignments for Salaspermic acid have been accomplished through the application of 1D and 2D nmr spectral techniques, and 13C-nmr assignments for celastrol [3] have been revised.

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