Sarcandrolide D

CAS# 1207185-03-2

Sarcandrolide D

2D Structure

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Sarcandrolide D: 5mg $886 In Stock
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Quality Control of Sarcandrolide D

3D structure

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Sarcandrolide D

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Chemical Properties of Sarcandrolide D

Cas No. 1207185-03-2 SDF Download SDF
PubChem ID 44627383 Appearance Powder
Formula C37H42O12 M.Wt 678.7
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES CC=C(C)C(=O)OCC1(C2CC2C3(C1CC4=C(C(=O)OC45C3CC6(C7CC7C8(C6=C5C9=C(C(=O)OC9(C8O)O)C)C)O)COC(=O)C)C)O
Standard InChIKey FYTGVSJFROTUKO-FFTXOPGASA-N
Standard InChI InChI=1S/C37H42O12/c1-7-14(2)28(39)47-13-35(44)22-8-19(22)32(5)23(35)10-18-17(12-46-16(4)38)30(41)48-36(18)24(32)11-34(43)21-9-20(21)33(6)27(34)26(36)25-15(3)29(40)49-37(25,45)31(33)42/h7,19-24,31,42-45H,8-13H2,1-6H3/b14-7+/t19-,20-,21+,22+,23-,24+,31-,32+,33+,34+,35+,36+,37+/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Sarcandrolide D

The herbs of Sarcandra glabra.

Biological Activity of Sarcandrolide D

In vitro

Cytotoxic sesquiterpenoids from Sarcandra glabra.[Reference: WebLink]

Tetrahedron, 2013, 69(2):564---569.


METHODS AND RESULTS:
Five new sesquiterpenoid dimers, sarcandrolides F−J (1−5), three new sesquiterpenoid monomers (6−8), and 14 known sesquiterpenoids, were isolated from the whole plants of Sarcandra glabra. The absolute configurations of compounds 1−5 were established by the CD exciton chirality method.
CONCLUSIONS:
Compound 1 represents the first example of a lindenane-type sesquiterpenoid dimer bearing a hydroperoxy group at C-5. Compounds 1 and 3 exhibited cytotoxicity against the HL-60 cell line with IC50 values of 0.03 and 1.2 μM, respectively.

Sarcandrolide D Dilution Calculator

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Sarcandrolide D Molarity Calculator

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Preparing Stock Solutions of Sarcandrolide D

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.4734 mL 7.367 mL 14.7341 mL 29.4681 mL 36.8351 mL
5 mM 0.2947 mL 1.4734 mL 2.9468 mL 5.8936 mL 7.367 mL
10 mM 0.1473 mL 0.7367 mL 1.4734 mL 2.9468 mL 3.6835 mL
50 mM 0.0295 mL 0.1473 mL 0.2947 mL 0.5894 mL 0.7367 mL
100 mM 0.0147 mL 0.0737 mL 0.1473 mL 0.2947 mL 0.3684 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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