ScholaricineCAS# 99694-90-3 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 99694-90-3 | SDF | Download SDF |
| PubChem ID | 14707746 | Appearance | Powder |
| Formula | C20H24N2O4 | M.Wt | 356.4 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | methyl (1R,11S,12R,17S)-6-hydroxy-12-[(1S)-1-hydroxyethyl]-8,14-diazapentacyclo[9.5.2.01,9.02,7.014,17]octadeca-2(7),3,5,9-tetraene-10-carboxylate | ||
| SMILES | CC(C1CN2CCC34C2CC1C(=C3NC5=C4C=CC=C5O)C(=O)OC)O | ||
| Standard InChIKey | GNCUCBQZLQLSOF-KJPXCLDGSA-N | ||
| Standard InChI | InChI=1S/C20H24N2O4/c1-10(23)12-9-22-7-6-20-13-4-3-5-14(24)17(13)21-18(20)16(19(25)26-2)11(12)8-15(20)22/h3-5,10-12,15,21,23-24H,6-9H2,1-2H3/t10-,11-,12+,15-,20+/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
The herbs of Bothrocaryum controversum
| Description | 1. Scholaricine reverses multidrug resistance in vincristine-resistant KB cells. |
Scholaricine Dilution Calculator
Scholaricine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.8058 mL | 14.0292 mL | 28.0584 mL | 56.1167 mL | 70.1459 mL |
| 5 mM | 0.5612 mL | 2.8058 mL | 5.6117 mL | 11.2233 mL | 14.0292 mL |
| 10 mM | 0.2806 mL | 1.4029 mL | 2.8058 mL | 5.6117 mL | 7.0146 mL |
| 50 mM | 0.0561 mL | 0.2806 mL | 0.5612 mL | 1.1223 mL | 1.4029 mL |
| 100 mM | 0.0281 mL | 0.1403 mL | 0.2806 mL | 0.5612 mL | 0.7015 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
Featured Products
- 14-Benzoylneoline
Catalog No.:BCN6493
CAS No.:99633-05-3
- Ro 19-4603
Catalog No.:BCC7228
CAS No.:99632-94-7
- Uncinatone
Catalog No.:BCN4547
CAS No.:99624-92-7
- ent-3beta,18-Dihydroxylabda-8(17),13E-dien-15-oic acid
Catalog No.:BCN7669
CAS No.:99624-39-2
- Kazinol A
Catalog No.:BCN3388
CAS No.:99624-28-9
- Kazinol B
Catalog No.:BCN4538
CAS No.:99624-27-8
- Isothymonin
Catalog No.:BCN3393
CAS No.:99615-01-7
- Leucanthogenin
Catalog No.:BCN7932
CAS No.:99615-00-6
- Ondansetron
Catalog No.:BCC5043
CAS No.:99614-02-5
- Ondansetron HCl
Catalog No.:BCC2493
CAS No.:99614-01-4
- Sertaconazole nitrate
Catalog No.:BCC4716
CAS No.:99592-39-9
- Sertaconazole
Catalog No.:BCC9146
CAS No.:99592-32-2
New Products
- Rotigotine
Catalog No.:BCC1907
CAS No.:99755-59-6
- Droxinostat
Catalog No.:BCC2157
CAS No.:99873-43-5
- Kaempferol 3-O-arabinoside
Catalog No.:BCN4541
CAS No.:99882-10-7
- Isoboonein acetate
Catalog No.:BCN4542
CAS No.:99891-77-7
- RGD (Arg-Gly-Asp) Peptides
Catalog No.:BCC5349
CAS No.:99896-85-2
- 3-(3,4-Dihydroxyphenyl)-1-n-propylpyrrolidine hydrobromide
Catalog No.:BCN8535
CAS No.:99933-30-9
- Bullatantriol
Catalog No.:BCN4543
CAS No.:99933-32-1
- Isoboonein
Catalog No.:BCN4545
CAS No.:99946-04-0
- Z-VDVAD-FMK
Catalog No.:BCC1138
CAS No.:N/A
- Acetyl Perisesaccharide C
Catalog No.:BCN8666
CAS No.:110764-09-5
- Dihydroartemisinic acid
Catalog No.:BCN8547
CAS No.:85031-59-0
- Rhein-8-glucoside
Catalog No.:BCN8548
CAS No.:34298-86-7
Strychnan and secoangustilobine A type alkaloids from Alstonia spatulata. Revision of the C-20 configuration of scholaricine.[Pubmed:21043460]
J Nat Prod. 2010 Nov 29;73(11):1891-7.
A total of 25 alkaloids were isolated from the leaf and stem-bark extracts of Alstonia spatulata, of which five are new alkaloids of the strychnan type (alstolucines A-E, 1-5) and the other, a new alkaloid of the secoangustilobine A type (alstolobine A, 6). The structures of these alkaloids were established using NMR and MS analysis and, in the case of alstolucine B (2), also confirmed by X-ray diffraction analysis. A reinvestigation of the stereochemical assignment of Scholaricine (13) by NMR and X-ray analyses indicated that the configuration at C-20 required revision. Alkaloids 1, 2, 6, 7, 9, 10, and 13 reversed multidrug resistance in vincristine-resistant KB cells.
Scholaricine,99694-90-3,Natural Products, buy Scholaricine , Scholaricine supplier , purchase Scholaricine , Scholaricine cost , Scholaricine manufacturer , order Scholaricine , high purity Scholaricine
