Stauntosaponin ACAS# 1417887-91-2 |
Quality Control & MSDS
3D structure
Package In Stock
Number of papers citing our products
| Cas No. | 1417887-91-2 | SDF | Download SDF |
| PubChem ID | 71525042 | Appearance | Powder |
| Formula | C28H38O7 | M.Wt | 486.60 |
| Type of Compound | Steroids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | (2R,3R,4R,6R)-6-[[(1R,4R,5R,8S,16S,19S,22R)-5,19-dimethyl-15,18,20-trioxahexacyclo[14.5.1.01,14.04,13.05,10.019,22]docosa-9,11,13-trien-8-yl]oxy]-4-methoxy-2-methyloxan-3-ol | ||
| SMILES | CC1C(C(CC(O1)OC2CCC3(C4CCC56COC7(C5C(CO7)OC6=C4C=CC3=C2)C)C)OC)O | ||
| Standard InChIKey | KNFHQIUXHMJLPI-IXHFUHRASA-N | ||
| Standard InChI | InChI=1S/C28H38O7/c1-15-23(29)20(30-4)12-22(33-15)34-17-7-9-26(2)16(11-17)5-6-18-19(26)8-10-28-14-32-27(3)24(28)21(13-31-27)35-25(18)28/h5-6,11,15,17,19-24,29H,7-10,12-14H2,1-4H3/t15-,17+,19+,20-,21-,22+,23-,24-,26+,27-,28+/m1/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Stauntosaponin A and stauntosaponin B show moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 uM, respectively. |
| Targets | Sodium Channel | ATPase | Potassium Channel |
| In vitro | Two secopregnane-type steroidal glycosides from Cynanchum stauntonii (Decne.) Schltr.ex Levl.[Reference: WebLink]Phytochemistry Letters, 2012, 5(2):304-308.
|
Stauntosaponin A Dilution Calculator
Stauntosaponin A Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.0551 mL | 10.2754 mL | 20.5508 mL | 41.1015 mL | 51.3769 mL |
| 5 mM | 0.411 mL | 2.0551 mL | 4.1102 mL | 8.2203 mL | 10.2754 mL |
| 10 mM | 0.2055 mL | 1.0275 mL | 2.0551 mL | 4.1102 mL | 5.1377 mL |
| 50 mM | 0.0411 mL | 0.2055 mL | 0.411 mL | 0.822 mL | 1.0275 mL |
| 100 mM | 0.0206 mL | 0.1028 mL | 0.2055 mL | 0.411 mL | 0.5138 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Albatrelin C
Catalog No.:BCN7591
CAS No.:1417805-17-4
- Albatrelin A
Catalog No.:BCN7626
CAS No.:1417805-15-2
- Exendin-4
Catalog No.:BCC1568
CAS No.:141758-74-9
- SDZ SER 082 fumarate
Catalog No.:BCC6994
CAS No.:1417343-80-6
- MM-102
Catalog No.:BCC4551
CAS No.:1417329-24-8
- Exenatide acetate
Catalog No.:BCN8514
CAS No.:141732-76-5
- H-DL-Phe(4-Cl)-OMe.HCl
Catalog No.:BCC3175
CAS No.:14173-40-1
- H-Phe(4-Cl)-OH
Catalog No.:BCC3171
CAS No.:14173-39-8
- RI-2
Catalog No.:BCC6424
CAS No.:1417162-36-7
- Faropenem daloxate
Catalog No.:BCC1571
CAS No.:141702-36-5
- Galanin (2-29) (rat)
Catalog No.:BCC5763
CAS No.:141696-11-9
- NPEC-caged-D-AP5
Catalog No.:BCC7895
CAS No.:1416943-27-5
- Endomorphin-2
Catalog No.:BCC5697
CAS No.:141801-26-5
- NMS-873
Catalog No.:BCC4977
CAS No.:1418013-75-8
- LMK 235
Catalog No.:BCC2421
CAS No.:1418033-25-6
- Minaxin C
Catalog No.:BCN7656
CAS No.:1418150-06-7
- EI1
Catalog No.:BCC4044
CAS No.:1418308-27-6
- Magnoloside D
Catalog No.:BCN8062
CAS No.:1418309-03-1
- Fmoc-Cys(pMeOBzl)-OH
Catalog No.:BCC3477
CAS No.:141892-41-3
- H-HoTyr-OH.HBr
Catalog No.:BCC3245
CAS No.:141899-12-9
- 4-Hydroxyphenylacetonitrile
Catalog No.:BCN6905
CAS No.:14191-95-8
- Pimentol
Catalog No.:BCN2714
CAS No.:141913-95-3
- Ginsenoyne K
Catalog No.:BCN3953
CAS No.:141947-42-4
- Ginsenoside Rg3
Catalog No.:BCN1068
CAS No.:14197-60-5
Two secopregnane-type steroidal glycosides from Cynanchum stauntonii (Decne.) Schltr.ex Levl.
Phytochemistry Letters, 2012, 5(2):304-308.
Two new steroid glycosides, Stauntosaponin A (1) and stauntosaponin B (2), were isolated from Cynanchum stauntonii (Decne.) Schltr.ex Levl. (Asclepiadaceae) together with five known compounds, anhydrohirundigenin monothevetoside, glaucogenin C mono-d-thevetoside, hirundoside A, cynatratoside A, and glaucogenin C. Stauntosaponins A and B were formulated as 3-O-β-d-oleandropyranosyl-14, 16: 15, 20: 18, 20-triepoxy-14, 15-secopregn-4, 6, 8(14)-triene (1) and 3-O-β-d-thevetopyranosyl-14, 16: 15, 20: 18, 20-triepoxy-14, 15-secopregn-4, 6, 8(14)-triene (2). Compounds 1 and 2 showed moderate inhibitory activities against Na+/K+-ATPase with IC50 values of 21 and 29 μM, respectively, whereas ouabain as a positive control displayed an IC50 value of 3.5 μM.
