Trillikamtoside RCAS# 2098642-71-6 |
Quality Control & MSDS
Package In Stock
Number of papers citing our products
| Cas No. | 2098642-71-6 | SDF | Download SDF |
| PubChem ID | N/A | Appearance | Powder |
| Formula | C49H72O25 | M.Wt | 1061.08 |
| Type of Compound | Steroids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Trillikamtoside R showed cytotoxic effect with an IC50 value of 4.92μM. |
| In vitro | Cytotoxic steroidal saponins from Trillium kamtschaticum.[Pubmed: 28454671 ]Bioorg Med Chem Lett. 2017 Jun 1;27(11):2267-2273.
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Trillikamtoside R Dilution Calculator
Trillikamtoside R Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 0.9424 mL | 4.7122 mL | 9.4244 mL | 18.8487 mL | 23.5609 mL |
| 5 mM | 0.1885 mL | 0.9424 mL | 1.8849 mL | 3.7697 mL | 4.7122 mL |
| 10 mM | 0.0942 mL | 0.4712 mL | 0.9424 mL | 1.8849 mL | 2.3561 mL |
| 50 mM | 0.0188 mL | 0.0942 mL | 0.1885 mL | 0.377 mL | 0.4712 mL |
| 100 mM | 0.0094 mL | 0.0471 mL | 0.0942 mL | 0.1885 mL | 0.2356 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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Cytotoxic steroidal saponins from Trillium kamtschaticum.[Pubmed:28454671]
Bioorg Med Chem Lett. 2017 Jun 1;27(11):2267-2273.
Eight new steroidal saponins, trillikamtosides K-R (1-8), along with three known analogues, were isolated from the whole plants of Trillium kamtschaticum. Their structures were unambiguously established by interpretation of spectroscopic data (MS and NMR) and chemical methods. Compound 1 had a rare aglycone featuring a skeleton of 16-oxaandrost-5-en-3-ol-17-one, which was reported for the first time. The isolated saponins were tested for cytotoxicities against HCT116 cells, and Trillikamtoside R (8) was found to show the most cytotoxic effect with an IC50 value of 4.92muM.
