Vomifoliol

CAS# 23526-45-6

Vomifoliol

2D Structure

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3D structure

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Vomifoliol

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Chemical Properties of Vomifoliol

Cas No. 23526-45-6 SDF Download SDF
PubChem ID 5280462 Appearance Powder
Formula C13H20O3 M.Wt 224.3
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
Chemical Name (4S)-4-hydroxy-4-[(E,3R)-3-hydroxybut-1-enyl]-3,5,5-trimethylcyclohex-2-en-1-one
SMILES CC1=CC(=O)CC(C1(C=CC(C)O)O)(C)C
Standard InChIKey KPQMCAKZRXOZLB-KOIHBYQTSA-N
Standard InChI InChI=1S/C13H20O3/c1-9-7-11(15)8-12(3,4)13(9,16)6-5-10(2)14/h5-7,10,14,16H,8H2,1-4H3/b6-5+/t10-,13-/m1/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Vomifoliol

The herbs of Vitis vinifera

Biological Activity of Vomifoliol

Description1. Vomifoliol is most likely the immediate precursor of dehydrovomifoliol, because of the organism converted abscisic acid (ABA), to dehydrovomifoliol as the major metabolise, and a cell-free extract exhibits vomifoliol dehydrogenase activity. 2. Vomifoliol and stigmasterol have anti-proliferative activity on human lung cancer cell lines.
TargetsNF-kB | HIF | VEGFR

Vomifoliol Dilution Calculator

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Vomifoliol Molarity Calculator

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Preparing Stock Solutions of Vomifoliol

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.4583 mL 22.2916 mL 44.5831 mL 89.1663 mL 111.4579 mL
5 mM 0.8917 mL 4.4583 mL 8.9166 mL 17.8333 mL 22.2916 mL
10 mM 0.4458 mL 2.2292 mL 4.4583 mL 8.9166 mL 11.1458 mL
50 mM 0.0892 mL 0.4458 mL 0.8917 mL 1.7833 mL 2.2292 mL
100 mM 0.0446 mL 0.2229 mL 0.4458 mL 0.8917 mL 1.1146 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Vomifoliol

Organic extractives from Mentha spp. honey and the bee-stomach: methyl syringate, vomifoliol, terpenediol I, hotrienol and other compounds.[Pubmed:20428087]

Molecules. 2010 Apr 22;15(4):2911-24.

The GC and GC/MS analyses of the solvent organic extractive from the stomach of the bees, having collected Mentha spp. nectar, revealed the presence of methyl syringate (6.6%), terpendiol I (5.0%) and Vomifoliol (3.0%) that can be attributed to the plant origin. Other major compounds from the bee-stomach were related to the composition of cuticular waxes and less to pheromones. Organic extractives from Mentha spp. honey were obtained by solvent-free headspace solid-phase microextraction (HS-SPME) and ultrasonic solvent extraction (USE) and analyzed by GC and GC/MS. The major honey headspace compounds were hotrienol (31.1%-38.5%), 2-methoxy-4-methylphenol (0.5-6.0%), cis- and trans-linalool oxides (0.9-2.8%), linalool (1.0-3.1%) and neroloxide (0.9-1.9%). Methyl syringate was the most abundant compound (38.3-56.2%) in the honey solvent extractives followed by Vomifoliol (7.0-26.6%). Comparison of the honey organic extractives with the corresponding bee-stomach extractive indicated that methyl syringate and vomofoliol were transferred to the honey while terpendiol I was partially transformed to hotrienol in ripened honey.

Screening of natural organic volatiles from Prunus mahaleb L. honey: coumarin and vomifoliol as nonspecific biomarkers.[Pubmed:21407151]

Molecules. 2011 Mar 16;16(3):2507-18.

Headspace solid-phase microextraction (HS-SPME; PDMS/DVB fibre) and ultrasonic solvent extraction (USE; solvent A: pentane and diethyl ether (1:2 v/v), solvent B: dichloromethane) followed by gas chromatography and mass spectrometry (GC, GC-MS) were used for the analysis of Prunus mahaleb L. honey samples. Screening was focused toward chemical composition of natural organic volatiles to determine if it is useful as a method of determining honey-sourcing. A total of 34 compounds were identified in the headspace and 49 in the extracts that included terpenes, norisoprenoids and benzene derivatives, followed by minor percentages of aliphatic compounds and furan derivatives. High Vomifoliol percentages (10.7%-24.2%) in both extracts (dominant in solvent B) and coumarin (0.3%-2.4%) from the extracts (more abundant in solvent A) and headspace (0.9%-1.8%) were considered characteristic for P. mahaleb honey and highlighted as potential nonspecific biomarkers of the honey's botanical origin. In addition, comparison with P. mahaleb flowers, leaves, bark and wood volatiles from our previous research revealed common compounds among norisoprenoids and benzene derivatives.

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