ZarzissineCAS# 160568-14-9 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 160568-14-9 | SDF | Download SDF |
| PubChem ID | 6400641 | Appearance | Powder |
| Formula | C5H5N5 | M.Wt | 135.1 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1H-imidazo[4,5-d]pyridazin-2-amine | ||
| SMILES | C1=C2C(=CN=N1)N=C(N2)N | ||
| Standard InChIKey | BUYBPEINWQQOFV-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C5H5N5/c6-5-9-3-1-7-8-2-4(3)10-5/h1-2H,(H3,6,9,10) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Zarzissine exhibits cytotoxicity against three human and murine tumor cell lines. |
Zarzissine Dilution Calculator
Zarzissine Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 7.4019 mL | 37.0096 mL | 74.0192 mL | 148.0385 mL | 185.0481 mL |
| 5 mM | 1.4804 mL | 7.4019 mL | 14.8038 mL | 29.6077 mL | 37.0096 mL |
| 10 mM | 0.7402 mL | 3.701 mL | 7.4019 mL | 14.8038 mL | 18.5048 mL |
| 50 mM | 0.148 mL | 0.7402 mL | 1.4804 mL | 2.9608 mL | 3.701 mL |
| 100 mM | 0.074 mL | 0.3701 mL | 0.7402 mL | 1.4804 mL | 1.8505 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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[Chemical constitunents of seeds of Oroxylum indicum].[Pubmed:23672042]
Zhongguo Zhong Yao Za Zhi. 2013 Jan;38(2):204-7.
OBJECTIVE: To study the chemical constituents in the seeds of Oroxylum indicum. METHOD: Twenty compounds were isolated and purified by silica gel, and Sephadex LH-20 column chromatography, and their structures were determined by spectroscopic analysis including NMR and MS. RESULT: Twenty compounds were isolated and identified as oroxin A (1), oroxin B (2), chrysin (3), baicalein (4), quercetin (5), apigenin (6), kaempferol (7), quercetin-3-O-ara-binopyranoside (8), lupeol C9), lup-20 (29)-ene-2alpha,3beta-diol (10), pinosylvin (11), dihydropinosylvin (12), cholest-5-ene-3, 7-diol (13), rengyol (14), isorengyol (15), Zarzissine (16), (E) -pinosylvin-3-O-beta-D-glucopyranoside (17), adenosine (18), sitosterol (19) and daucosterol (20). CONCLUSION: Compounds 11-13 and 15-18 were obtained from the genus Oroxylum for the first time, and except compound 18, the remaining 6 compounds were obtained from the family Bignoniaceae for the first time.
Zarzissine, a new cytotoxic guanidine alkaloid from the Mediterranean sponge Anchinoe paupertas.[Pubmed:7807130]
J Nat Prod. 1994 Oct;57(10):1455-7.
From a CH2Cl2 extract of the Mediterranean sponge Anchinoe paupertas were isolated and characterized Zarzissine [2], a new 4,5-guanidino-pyridazine compound and the known p-hydroxybenzaldehyde [1]. The structure of Zarzissine [2] was elucidated by spectroscopic methods, including the application of a number of 2D nmr techniques. Biological activities of compounds 1 and 2 were also determined, with Zarzissine exhibiting cytotoxicity against three human and murine tumor cell lines.
