Zedoalactone A

CAS# 170384-82-4

Zedoalactone A

2D Structure

Catalog No. BCX0290----Order now to get a substantial discount!

Product Name & Size Price Stock
Zedoalactone A: 5mg $903 In Stock
Zedoalactone A: 10mg Please Inquire In Stock
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Zedoalactone A

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Chemical Properties of Zedoalactone A

Cas No. 170384-82-4 SDF Download SDF
PubChem ID N/A Appearance Powder
Formula C15H22O4 M.Wt 266.37
Type of Compound Sesquiterpenoids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Zedoalactone A Dilution Calculator

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Zedoalactone A Molarity Calculator

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Preparing Stock Solutions of Zedoalactone A

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.7542 mL 18.7709 mL 37.5418 mL 75.0835 mL 93.8544 mL
5 mM 0.7508 mL 3.7542 mL 7.5084 mL 15.0167 mL 18.7709 mL
10 mM 0.3754 mL 1.8771 mL 3.7542 mL 7.5084 mL 9.3854 mL
50 mM 0.0751 mL 0.3754 mL 0.7508 mL 1.5017 mL 1.8771 mL
100 mM 0.0375 mL 0.1877 mL 0.3754 mL 0.7508 mL 0.9385 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Zedoalactone A

Three new guaiane sesquiterpene lactones from rhizomes of Curcuma wenyujin.[Pubmed:23679107]

J Asian Nat Prod Res. 2013 Jul;15(7):723-30.

Three new guaiane sesquiterpene lactones (4S)-4-hydroxy-gweicurculactone (1), zedoalactone G (2), and (1R, 4R, 5S, 10S)-zedoalactone B (3), and three known guaiane sesquiterpene lactones, including zedoarolide B (4), zedoalactone B (5), and a new natural product (+)-Zedoalactone A (6), were isolated from the rhizomes of Curcuma wenyujin Y.H. Chen et C. Ling. The structures were elucidated by spectroscopic methods including 1D and 2D NMR and HR-ESI-MS. The absolute configuration of 2 was determined via the calculated electronic circular dichroism (ECD), whereas the absolute configurations of 1 and 3 were determined via the ECD data of the [Rh2(OCOCF3)4] complex and [Mo2(OAc)4] complex, respectively. The inhibitory effects of compounds 1-6 on nitric oxide production in lipopolysaccharide-activated macrophages were evaluated. All of them exhibited weak anti-inflammatory activity.

Sesquiterpenoids from Chloranthus multistachys.[Pubmed:23312365]

Phytochemistry. 2013 Apr;88:112-8.

An 8,9-seco-lindenane disesquiterpenoid, chloramultiol G, four eudesmane sesquiterpenoids, ent-(3R)-3-hydroxyatractylenolide III and multistalactones A-C, and four guaiane sesquiterpenoids, (1R,4S,5R,8S,10S)-Zedoalactone A and multistalactones D-F, along with 14 known compounds, were isolated from whole plant tissues of Chloranthus multistachys. Their structures were established by extensive NMR experiments in conjunction with mass spectrometry. Except for chloramultiol G, the absolute stereochemistries of the other eight were confirmed by single-crystal X-ray crystallography and CD spectra. Nine compounds were tested for cytotoxicity against five human tumor cell lines and for antifungal activity against four microorganisms in vitro, but all were inactive.

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