2-Ethyl-3-methylmaleimideCAS# 20189-42-8 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 20189-42-8 | SDF | Download SDF |
| PubChem ID | 29995 | Appearance | Powder |
| Formula | C7H9NO2 | M.Wt | 139.15 |
| Type of Compound | Alkaloids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 3-ethyl-4-methylpyrrole-2,5-dione | ||
| SMILES | CCC1=C(C(=O)NC1=O)C | ||
| Standard InChIKey | CUBICSJJYOPOIA-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C7H9NO2/c1-3-5-4(2)6(9)8-7(5)10/h3H2,1-2H3,(H,8,9,10) | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
2-Ethyl-3-methylmaleimide Dilution Calculator
2-Ethyl-3-methylmaleimide Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 7.1865 mL | 35.9324 mL | 71.8649 mL | 143.7298 mL | 179.6622 mL |
| 5 mM | 1.4373 mL | 7.1865 mL | 14.373 mL | 28.746 mL | 35.9324 mL |
| 10 mM | 0.7186 mL | 3.5932 mL | 7.1865 mL | 14.373 mL | 17.9662 mL |
| 50 mM | 0.1437 mL | 0.7186 mL | 1.4373 mL | 2.8746 mL | 3.5932 mL |
| 100 mM | 0.0719 mL | 0.3593 mL | 0.7186 mL | 1.4373 mL | 1.7966 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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The Allelopathic Activity of Extracts and Isolated from Spirulina platensis.[Pubmed:35744974]
Molecules. 2022 Jun 15;27(12):3852.
We determined the allelopathic effects of crude organic (hexane, ethyl acetate, and methanol) extracts of the cyanobacterial Spirulina platensis on barnyardgrass (Echinochloa crus-galli (L.) Beauv.) and Chinese amaranth (Amaranthus tricolor L.). The crude ethyl acetate extract showed the highest inhibitory activity and was subsequently fractionated by column chromatography into 23 fractions based on thin-layer chromatography band pattern similarities. Four concentrations (2000, 1000, 500, and 250 ppm) of each fraction were tested for their allelopathic activity. Fractions E6 and E13 exhibited the most significant inhibitory effects against Chinese amaranth. The constituents of the highly active E6F3-E6F5 fractions determined by GC-MS, chromatography, and spectroscopy included the fatty acids, gamma-linolenic acid 15, oleic acid 12, and predominantly palmitic acid 7; minor constituents included 2-Ethyl-3-methylmaleimide 9 and C(11) norisoprenoids (dihydroactinidiolide 10 and 4-oxo-beta-ionone 13). Isolation of E13 fraction by column chromatography revealed four C(13) norisoprenoids: 3-hydroxy-beta-ionone 17, 3-hydroxy-5alpha,6alpha-epoxy-beta-ionone 18, 3-hydroxy-5beta,6beta-epoxy-beta-ionone 19, and loliolide 20. Their structures were elucidated by NMR spectroscopy. All six isolated norisoprenoids inhibited seed germination and seedling growth of Chinese amaranth at concentrations of 250-1000 ppm. Allelochemicals from S. platensis could be utilized in the development of novel bioactive herbicides.
Isolation and identification of antialgal compounds from the leaves of Vallisneria spiralis L. by activity-guided fractionation.[Pubmed:16910120]
Environ Sci Pollut Res Int. 2006 Jul;13(4):233-7.
BACKGROUND, AIMS AND SCOPE: Vallisneria spiralis Linn., a common submerged macrophyte, is widely available in quiet waters of lakes, ponds, marshes and streams in Southeast Asia. V. spiralis plays a significant role not only in decreasing eutrophication of water body for its productivity, but also in inhibiting the growth of blue-green algae? The aim of the paper involves the isolation and identification of allelochemicals from extracts of V. spiralis by activity-guided fractionation and column chromatography. METHODS: Leaves of V. spiralis was washed free of debris, air-dried and refluxed in 95% EtOH. The extract was isolated using column chromatography and fractionation with antialgal activity. Potential allelochemicals were analyzed by high-resolution gas chromatography-mass spectrometry (HRGC-MS). RESULTS: Two fractions with strong antialgal activity were isolated using column chromatography and activity-guided fractionation from the extract of V. spiralis. 2-Ethyl-3-methylmaleimide, dihydroactinidiolide and 4-oxo-beta-Ionone were identified in the first fraction, and 3-hydroxy-5,6-epoxy-beta-ionone, loliolide, 6-hydroxy-3-oxo-alpha-ionone and an unknown compound in the second fraction. They had strong inhibitory effects on Microcystis aeruginosa Kutz. DISCUSSION: 2-Ethyl-3-methylmaleimide is a byproduct of photooxidation of chlorophyll, and five other compounds identified were derivatives of beta-carotene. HRGC-MS and derivatization technology were used to identify and confirm their molecular structures. The formula of the unknown compound was C16H19NO4. Metabolites of plant pigments had strong inhibitory activities on growth of algae. CONCLUSIONS: Six compounds had been identified in V. spiralis, among them, 2-Ethyl-3-methylmaleimide was the main allelochemical, and derivatives of ionone were also potential allelochemicals. RECOMMENDATIONS AND PERSPECTIVES: The results of our research could help us to study further mechanisms of inhibitory effect on algae and develop new potential antialgal substances.
2-Ethyl-3-methylmaleimide in Tokyo Bay sediments providing the first evidence for its formation from chlorophylls in the present photic and oxygenic zone.[Pubmed:12400681]
Biosci Biotechnol Biochem. 2002 Sep;66(9):1844-7.
Tokyo Bay bottom sediments were analyzed for 2-Ethyl-3-methylmaleimide, a degradation product of chlorophylls, which has been detected in ancient sediments. It was found in all sediments examined in concentrations of about 1 to 15 nmol/g- of dried sediment, and it was shown to be preserved for 100 years in the sediments. Its depth distribution agreed with that of the reported total organic carbon content of the sediments, reflecting a change in primary productivity. We concluded that this maleimide was produced under photic and oxygenic conditions in nature before the incorporation of photosynthesizing organisms into sediments.
