Cancer Research
Cancer is a term used to define a group of diseases in which abnormal cells divide without control, are able to invade neighboring tissues/organs and metastasize. Cancer has been characterized by six hallmarks; self sufficiency in proliferative growth signals, insensitivity to growth inhibitors, evasion of apoptosis, limitless replicative potential, ability to develop blood vessels (angiogenesis), and tissue invasion and metastasis.
Cancer Research Products Areas
Products for Cancer Research - Page 80
- Cat.No. Product Name Information/Activity
-
BCC7778
CD 2665
CD2665 is a selective RAR-beta/gamma antagonist, with Ki values of 110 nM, 306 nM for RARγ and RARβ, respectively.
-
BCC7783
ER 50891
187400-85-7
-
BCC7782
MM 11253
345952-44-5
-
BCC7679
BMS 453
166977-43-1
-
BCC6097
EC 23
EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.
-
BCC1572
Fenretinide
Synthetic retinoid; antiproliferative and antioxidant,Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells.
-
BCC3737
Bexarotene
Bexarotene (LGD1069) is a selective retinoid X receptors (RXR) agonist for the treatment of cutaneous T-cell lymphoma.
-
BCC7637
CD 3254
CD3254 a potent and selective retinoid-X-receptor (RXR) agonist.
-
BCC6110
Fluorobexarotene
Fluorobexarotene (compound 20) is a potent retinoid-X-receptor (RXR) agonist, with a Ki value of 12 nM and an EC50 value of 43 nM for RXRα receptor. Fluorobexarotene possesses an apparent RXR binding affinity that is 75% greater than Bexarotene.
-
BCC7681
SR 11237
146670-40-8
