Androgen Receptor
Androgen receptors (ARs) (dihydrotestosterone receptors) are nuclear hormone receptors of the NR3C class, which includes mineralocorticoid, progesterone and glucocorticoid receptors. ARs are expressed in bone marrow, mammary gland and prostate tissues.
Products for Androgen Receptor
- Cat.No. Product Name Information/Activity
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BCC7780
Cl-4AS-1
188589-66-4
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BCN2193
Testosterone
58-22-0
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BCC2481
Bicalutamide
Bicalutamide is a non-steroidal androgen receptor inhibitor.
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BCC4364
Flutamide
Flutamide is an antiandrogen drug, with its active metablolite binding at androgen receptor with Ki values of 55 nM, and primarily used to treat prostate cancer.
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BCC7811
PF 998425
1076225-27-8
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BCC6069
TFM-4AS-1
188589-61-9
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BCC1333
AIM-100
AIM-100 is a small molecule inhibitor of Ack1 with an IC50 of 24 nM
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BCC2491
Finasteride
Finasteride is an orally active testosterone 5-alpha-reductase inhibitor (Ki= 10 nM).
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BCC4070
GSK 650394
GSK 650394 is a novel SGK inhibitor with IC50 of 62 nM and 103 nM for SGK1 and SGK2 in the SPA assay respectively. GSK 650394 also inhibits influenza virus replication.
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BCN4037
Piplartine
Piperlongumine is a natural alkaloid isolated from Piper longum Linn, possesses ant-inflammatory, antibacterial, antiangiogenic, antioxidant, antitumor, and antidiabetic activities. Piperlongumine induces ROS, and induces apoptosis in cancer cell lines. Piperlongumine shows anti-cardiac fibrosis activity, suppresses myofibroblast transformation via suppression of the ERK1/2 signaling pathway.
