Arrhythmia Research

An arrhythmia (also known as cardiac dysrhythmia) is defined as an irregular heartbeat, and results from abnormal electrical activity in the heart. There are various different types of arrhythmia, often resulting in a heartbeat that is too fast (tachycardia) or too slow (bradycardia). Atrial and ventricular fibrillation, which are the most common cardiac arrhythmias, account for 10-20% of all deaths among adults in the Western world. The incidence of atrial fibrillation increases with age; it not only affects cardiac function, but also increases the risk of stroke and may worsen heart failure.

Arrhythmia Research Products Targets

Products for Arrhythmia Research - Page 3

  1. Cat.No. Product Name Information/Activity
  2. BCC7833 SR 58611A hydrochloride Amibegron hydrochloride is a selective β3-adrenoceptor agonist, with an EC50 of 3.5 nM for β-adrenoceptor in rat colon; Amibegron hydrochloride has anxiolytic and antidepressant activity. SR 58611A hydrochloride chemical structure
  3. BCC5878 ZD 2079 178600-17-4 ZD 2079 chemical structure
  4. BCC6852 ZD 7114 hydrochloride 129689-28-7 ZD 7114 hydrochloride chemical structure
  5. BCC7475 L-748,337 244192-94-7 L-748,337 chemical structure
  6. BCC7094 SR 59230A hydrochloride SR59230A hydrochloride is a potent, selective, and blood-brain barrier penetrating β3-adrenergic receptor antagonist with IC50s of 40, 408, and 648 nM for β3, β1, and β2 receptors, respectively. SR 59230A hydrochloride chemical structure
  7. BCC2399 Cesium chloride Potassium channel blocker; neuroprotective Cesium chloride chemical structure
  8. BCC6639 YS-035 hydrochloride 89805-39-0 YS-035 hydrochloride chemical structure
  9. BCC7286 Zatebradine hydrochloride Zatebradine (UL-FS-49 (free base)) is a potent inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels with an IC50 values 1.96 µM. Zatebradine blocks the slow inward current through human HCN1, HCN2, HCN3 and HCN4 channels, with IC50 values of 1.83 µM, 2.21 µM, 1.90 µM and 1.88 µM, respectively. Zatebradine hydrochloride chemical structure
  10. BCC6884 ZD 7288 ZD7288 is a selective hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker. ZD 7288 chemical structure
  11. BCC6978 2-APB 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3). 2-APB chemical structure

Items 21 to 30 of 183 total