Arrhythmia Research

An arrhythmia (also known as cardiac dysrhythmia) is defined as an irregular heartbeat, and results from abnormal electrical activity in the heart. There are various different types of arrhythmia, often resulting in a heartbeat that is too fast (tachycardia) or too slow (bradycardia). Atrial and ventricular fibrillation, which are the most common cardiac arrhythmias, account for 10-20% of all deaths among adults in the Western world. The incidence of atrial fibrillation increases with age; it not only affects cardiac function, but also increases the risk of stroke and may worsen heart failure.

Arrhythmia Research Products Targets

Products for Arrhythmia Research - Page 8

  1. Cat.No. Product Name Information/Activity
  2. BCC6255 ProTx I 484598-35-8 ProTx I chemical structure
  3. BCC5952 SNX 482 203460-30-4 SNX 482 chemical structure
  4. BCC7181 SR 33805 oxalate 121346-33-6 SR 33805 oxalate chemical structure
  5. BCC4747 Verapamil HCl Verapamil hydrochloride ((±)-Verapamil hydrochloride) is a calcium channel antagonist. Verapamil HCl chemical structure
  6. BCN2207 Ascorbic acid PROTAC EED degrader-1 is a PROTAC targeting EED with a pKD of 9.02. PROTAC EED degrader-1 is a polycomb repressive complex 2 (PRC2) inhibitor (pIC50=8.17) targeting the EED subunit. Ascorbic acid chemical structure
  7. BCC3783 Gabapentin Gabapentin (Neurontin) is a pharmaceutical drug, specifically a GABA analog. Gabapentin chemical structure
  8. BCN2175 Pregabalin 148553-50-8 Pregabalin chemical structure
  9. BCC7984 MaxiPost Flindokalner (BMS-204352) is a potassium channel modulator. Flindokalner is a positive modulator of all neuronal Kv7 channel subtypes expressed in HEK293 cells. Flindokalner is also a large conductance calcium-activated K channel (BKca) positive modulator. Flindokalner shows a negative modulatory activity at Kv7.1 channels (Ki=3.7 μM), and acts as a negative modulator of GABAA receptors. Flindokalner shows anxiolytic efficacy in vivo. MaxiPost chemical structure
  10. BCC7448 BMS 191011 BMS-191011 (BMS-A) is an opener of the large-conductance, Ca2++-activated potassium (maxi-K) channel, effective in stroke models. BMS 191011 chemical structure
  11. BCC7526 CyPPA 73029-73-9 CyPPA chemical structure

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