Immunology Research
Immunology is a branch of science that studies all aspects of the immune system, ranging from normal physiological functioning through to malfunctions which can lead to immunological diseases. Disorders that result from aberrant activation of the immune system are termed autoimmune diseases.
Immunology Research Products Areas
Products for Immunology Research - Page 18
- Cat.No. Product Name Information/Activity
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BCC6985
NF 023
104869-31-0
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BCC7404
NF 110
111150-22-2
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BCC7367
NF 157
NF157 is a highly selective nanomolar P2Y11 antagonist with a pKi of 7.35. The IC50s are 463 nM, 1811 µM, 170 µM for P2Y11 (Ki=44.3 nM), P2Y1 (Ki=187 µM), P2Y2 (Ki=28.9 µM), respectively. NF157, significantly reduces expression of metalloproteinase (MMP)-3, MMP-13, can be used in the treatment of osteoarthritis (OA).
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BCC6964
NF 279
202983-32-2
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BCC7043
NF 449
Highly selective P2X<sub>1</sub> antagonist
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BCC6725
PPADS tetrasodium salt
PPADS tetrasodiuma is a non-selective P2X receptor antagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 with IC50s ranging from 1 to 2.6 μM. PPADS tetrasodiuma blocks native P2Y2-like (IC50~0.9 mM) and recombinant P2Y4 (IC50~15 mM) receptors. PPADS tetrasodiuma is an inhibitor of the reverse mode of the Na/Ca²⁺exchanger in guinea pig airway smooth muscle.
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BCC6749
iso-PPADS tetrasodium salt
P2X antagonist
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BCC7015
PPNDS
1021868-77-8
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BCC7276
Ro 0437626
134362-79-1
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BCC6157
Ro 51
1050670-85-3
