Arthritis Research

Arthritis is an inflammatory disease of the joints, including the synovium, cartilage, bone, and supporting tissues. It is the leading cause of disability in the US and there are over 100 different types of the disease. The most common types of arthritis are osteoarthritis, rheumatoid arthritis and gout.

Arthritis Research Products Targets

Products for Arthritis Research - Page 7

  1. Cat.No. Product Name Information/Activity
  2. BCC1184 Dexamethasone (DHAP) Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18L expression on monocytes. Dexamethasone (DHAP) chemical structure
  3. BCN2192 Hydrocortisone Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland. Hydrocortisone chemical structure
  4. BCC8088 AEG 3482 63735-71-7 AEG 3482 chemical structure
  5. BCC8089 BI 78D3 BI-78D3 functions as a substrate competitive inhibitor of JNK, inhibit the JNK kinase activity (IC50=280 nM). BI 78D3 chemical structure
  6. BCC7982 CEP 1347 156177-65-0 CEP 1347 chemical structure
  7. BCC8085 c-JUN peptide 610273-01-3 c-JUN peptide chemical structure
  8. BCC8093 IQ 3 312538-03-7 IQ 3 chemical structure
  9. BCC5777 JIP-1 (153-163) 438567-88-5 JIP-1 (153-163) chemical structure
  10. BCC2474 SP 600125 JNK inhibitor; prevents BMP9-induced osteogenic differentiation of MSCs,SP600125 is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM in cell-free assays, respectively; 10-fold greater selectivity against MKK4, 25-fold greater selectivity against MKK3, MKK6, PKB, and PKCα, and 100-fold selectivity against ERK2, p38, Chk1, EGFR etc. SP 600125 chemical structure
  11. BCC7999 SR 3576 1164153-22-3 SR 3576 chemical structure

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