Arthritis Research
Arthritis is an inflammatory disease of the joints, including the synovium, cartilage, bone, and supporting tissues. It is the leading cause of disability in the US and there are over 100 different types of the disease. The most common types of arthritis are osteoarthritis, rheumatoid arthritis and gout.
Arthritis Research Products Targets
- Matrix Metalloprotease (16)
- Cell Adhesion Molecule (21)
- Leukotriene and Related Receptor (13)
- Others (7)
- Glucocorticoid Receptor (9)
- Cyclooxygenase (24)
- Complement (2)
- Focal Adhesion Kinase (4)
- Chemokine CXC Receptor (9)
- Chemokine CC Receptor (13)
- p38 MAPK (16)
- Janus N-terminal Kinase (12)
- Calcium-Sensitive Protease Modulator (12)
- Rho-Kinases (9)
- NO donors and precursors (9)
- nNOS (5)
- iNOS (11)
- eNOS (1)
- Cytokine (15)
Products for Arthritis Research - Page 7
- Cat.No. Product Name Information/Activity
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BCC1184
Dexamethasone (DHAP)
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist. Dexamethasone also significantly decreases CD11b, CD18, and CD62L expression on neutrophils, and CD11b and CD18L expression on monocytes.
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BCN2192
Hydrocortisone
Hydrocortisone is a steroid hormone or glucocorticoid produced by the adrenal gland.
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BCC8088
AEG 3482
63735-71-7
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BCC8089
BI 78D3
BI-78D3 functions as a substrate competitive inhibitor of JNK, inhibit the JNK kinase activity (IC50=280 nM).
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BCC7982
CEP 1347
156177-65-0
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BCC8085
c-JUN peptide
610273-01-3
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BCC8093
IQ 3
312538-03-7
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BCC5777
JIP-1 (153-163)
438567-88-5
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BCC2474
SP 600125
JNK inhibitor; prevents BMP9-induced osteogenic differentiation of MSCs,SP600125 is a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM in cell-free assays, respectively; 10-fold greater selectivity against MKK4, 25-fold greater selectivity against MKK3, MKK6, PKB, and PKCα, and 100-fold selectivity against ERK2, p38, Chk1, EGFR etc.
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BCC7999
SR 3576
1164153-22-3


