Arthritis Research

Arthritis is an inflammatory disease of the joints, including the synovium, cartilage, bone, and supporting tissues. It is the leading cause of disability in the US and there are over 100 different types of the disease. The most common types of arthritis are osteoarthritis, rheumatoid arthritis and gout.

Arthritis Research Products Targets

Products for Arthritis Research - Page 5

Cat.No. Product Name Information/Activity
BCC6161 (±)-CPSI 1306 (±)-CPSI-1306 is an orally available antagonist of macrophage migration inhibitory factor (MIF).
BCC5914 ER 27319 maleate 1204480-26-1
BCC2096 Gabexate mesylate Gabexate mesylate is a Factor X inhibitor; serine protease inhibitor .
BCC5203 VGX-1027 VGX-1027(GIT27) is an isoxazole compound that exhibits various immunomodulatory properties; reduce the secretion of IL-1beta, TNF-alpha and IL-10 from purified murine macrophages.
BCC5773 10Z-Hymenialdisine 82005-12-7
BCC6365 iMDK 881970-80-5
BCC6023 4-IPP 4-IPP (4-Iodo-6-phenylpyrimidine) is a specific suicide substrate and irreversible inhibitor of macrophage migration inhibitory factor (MIF).
BCC5427 ISO-1 ISO-1 is a macrophage migration inhibitory factor (MIF) antagonist with an IC50 of 7 μM.
BCC7960 (D)-(+)-Neopterin D-(+)-Neopterin, a catabolic product of guanosine triphosphate (GTM), serves as a marker of cellular immune system activation.
BCC5086 Pirfenidone Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities.