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Cat.No. Product Name Information/Activity

BCC6985 NF 023 104869-31-0 NF 023 chemical structure

BCC7404 NF 110 111150-22-2 NF 110 chemical structure

BCC7367 NF 157 NF157 is a highly selective nanomolar P2Y11 antagonist with a pKi of 7.35. The IC50s are 463 nM, 1811 µM, 170 µM for P2Y11 (Ki=44.3 nM), P2Y1 (Ki=187 µM), P2Y2 (Ki=28.9 µM), respectively. NF157, significantly reduces expression of metalloproteinase (MMP)-3, MMP-13, can be used in the treatment of osteoarthritis (OA). NF 157 chemical structure

BCC6964 NF 279 202983-32-2 NF 279 chemical structure

BCC7043 NF 449 Highly selective P2X<sub>1</sub> antagonist NF 449 chemical structure

BCC6725 PPADS tetrasodium salt PPADS tetrasodiuma is a non-selective P2X receptor antagonist. PPADS tetrasodiuma blocks recombinant P2X1, -2, -3, -5 with IC50s ranging from 1 to 2.6 μM. PPADS tetrasodiuma blocks native P2Y2-like (IC50~0.9 mM) and recombinant P2Y4 (IC50~15 mM) receptors. PPADS tetrasodiuma is an inhibitor of the reverse mode of the Na/Ca²⁺exchanger in guinea pig airway smooth muscle. PPADS tetrasodium salt chemical structure

BCC6749 iso-PPADS tetrasodium salt P2X antagonist iso-PPADS tetrasodium salt chemical structure

BCC7015 PPNDS 1021868-77-8 PPNDS chemical structure

BCC7276 Ro 0437626 134362-79-1 Ro 0437626 chemical structure

BCC6157 Ro 51 1050670-85-3 Ro 51 chemical structure

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