Neuroscience Research

Neuroscience is the study of the nervous system - one of the major mammalian systems responsible for sustaining life. The central nervous system (CNS) and peripheral nervous system (PNS) work in concert to coordinate basic functions such as moving and breathing, as well as 'higher order' functions including thought, speech and emotion.

Neuroscience Research Products Areas

Products for Neuroscience Research - Page 133

Cat.No. Product Name Information/Activity
BCC5906 Astressin 2B 681260-70-8
BCC5867 K 41498 434938-41-7
BCC6224 A 412997 dihydrochloride Selective D<sub>4</sub> agonist
BCC7293 ABT 724 trihydrochloride ABT-724 trihydrochloride is a potent and highly selective dopamine D4 receptor agonist with an EC50 of 12.4 nM for human dopamine D4 receptor. ABT-724 trihydrochloride is a potent partial agonist at the rat D4 (EC50 of 14.3 nM) and the ferret D4 receptor (EC50 of 23.2 nM), and has no effect on dopamine D1, D2, D3, or D5 receptors. ABT-724 trihydrochloride could be useful for the treatment of erectile dysfunction and has favorable side-effect profile.
BCC6919 PD 168077 maleate PD-168077 maleate is a selective dopamine D4 receptor agonist, with a Ki of 9 nM.
BCC7330 Ro 10-5824 dihydrochloride Ro 10-5824 dihydrochloride is a selective dopamine D4 receptor partial agonist, with Ki of 5.2 nM.
BCC2054 WAY-100635 maleate salt WAY-100635 maleate salt is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 value of 0.91 nM and Ki value of 0.39 nM. WAY-100635 maleate salt has pIC50 values for 5-HT1A and α1-adrenergic receptors of 8.9 and 6.6, respectively. WAY-100635 maleate salt is also a potent dopamine D4 receptor agonist.
BCC7440 Fananserin Fananserin (RP 62203) is an orally bioavailable, potent and selective 5-hydroxytryptamine2 (5-HT2) receptor antagonist, with a Ki of 0.37 nM for the rat 5-HT2A receptor. Fananserin also is a selective dopamine D4 receptor antagonist, with a Ki of 2.93 nM for the human dopamine D4 receptor.
BCC5696 L-741,742 hydrochloride 874882-93-6
BCC5695 L-745,870 trihydrochloride 866021-03-6