Huntington's Disease Research

Huntington's disease is a neurodegenerative disease characterized by cognitive decline and motor dysfunction. It is a genetic disorder which results in the production of mutant huntingtin protein (mHtt). This protein aggregates in the cell cytoplasm and nucleus, affecting cellular function.

Huntington's Disease Research Products Targets

Products for Huntington's Disease Research

Cat.No. Product Name Information/Activity
BCC4316 CGS 21680 HCl CGS 21680 Hydrochloride is a selective adenosine A2A receptor agonist with a Ki of 27 nM.
BCC7163 CV 1808 53296-10-9
BCC6237 LUF 5834 333962-91-7
BCC7640 8-(3-Chlorostyryl)caffeine 147700-11-6
BCC7815 ANR 94 Adenosine A<sub>2A </sub>antagonist
BCC3798 Istradefylline (KW-6002) Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease.
BCC7977 Lu AA 47070 913842-25-8
BCC7372 SCH 442416 316173-57-6
BCC7306 SCH 58261 SCH 58261 is a potent, selective and competitive antagonist of adenosine A2A receptor with an IC50 of 15 nM, and displays 323-, 53- and 100-fold more selective for A2A receptor than A1, A2B, and A3 receptors, respectively.
BCC6165 TC-G 1004 1061747-72-5