Alzheimer's Disease Research

Alzheimer's disease (AD), the most common type of dementia, is an irreversible and progressive neurodegenerative disorder causing cognitive and functional impairment. It is characterized by formation of protein aggregates and progressive loss of neurons in the central nervous system (CNS). The symptoms of AD include short-term memory loss, confusion, irritability, aggression and mood swings, progressing to long-term memory deficit, withdrawal from social interactions and subsequently a loss in higher central functioning.

Alzheimer's Disease Research Products Targets

Products for Alzheimer's Disease Research - Page 18

Cat.No. Product Name Information/Activity
BCC7970 Lithium carbonate 554-13-2
BCC3898 MeBIO 667463-95-8
BCC7208 NSC 693868 40254-90-8
BCC3650 SB 216763 SB 216763 is potent, selective and ATP-competitive GSK-3 inhibitor with IC50s of 34.3 nM for both GSK-3α and GSK-3β.
BCC3651 SB 415286 Potent, selective GSK-3 inhibitor,SB415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β.
BCC6146 TC-G 24 1257256-44-2
BCC6074 TCS 2002 1005201-24-0
BCC2443 TCS 21311 TCS 21311 (NIBR3049) is a potent, highly selective JAK3 inhibitor with an IC50 of 8 nM, it displays >100-fold selectivity over JAK1, JAK2 and TYK2. TCS 21311 (NIBR3049) inhibits PKCα, PKCθ, and GSK3β with IC50s of 13, 68, and 3 nM, respectively.
BCC5817 2B-(SP) 186901-17-7
BCC5747 Phospho-Glycogen Synthase Peptide-2 (substrate) 851366-97-7