Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 61

  1. Cat.No. Product Name Information/Activity
  2. BCC1312 5-Iodotubercidin 5-Iodotubercidin (NSC 113939), an ATP mimetic, is a potent adenosine kinase inhibitor with an IC50 of 26 nM. 5-Iodotubercidin (NSC 113939) initiates glycogen synthesis in isolated hepatocytes by causing inactivation of phosphorylase and activation of glycogen synthase. 5-Iodotubercidin (NSC 113939) also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2, PKC and Haspin. 5-Iodotubercidin chemical structure
  3. BCC7516 NBMPR 38048-32-7 NBMPR chemical structure
  4. BCC8024 Rose Bengal Potent VGlut and VMAT inhibitor; cell permeable Rose Bengal chemical structure
  5. BCC7799 FFN 511 1004548-96-2 FFN 511 chemical structure
  6. BCC5801 GR 73632 GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals. GR 73632 chemical structure
  7. BCC5923 Hemokinin 1 (human) 491851-53-7 Hemokinin 1 (human) chemical structure
  8. BCC5774 Hemokinin 1 (mouse) Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively. Hemokinin 1 (mouse) chemical structure
  9. BCC6960 [Sar9,Met(O2)11]-Substance P [Sar9,Met(O2)11]-Substance P is a tachykinin NK1 receptor selective agonist. [Sar9,Met(O2)11]-Substance P chemical structure
  10. BCC7509 CP 96345 132746-60-2 CP 96345 chemical structure
  11. BCC6016 CP 99994 dihydrochloride 145148-39-6 CP 99994 dihydrochloride chemical structure

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