Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 53

  1. Cat.No. Product Name Information/Activity
  2. BCC7123 Indatraline hydrochloride 96850-13-4 Indatraline hydrochloride chemical structure
  3. BCC7402 Lofepramine Lofepramine (Lopramine) is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. The antidepressant activity of Lofepramine stems from the facilitation of noradrenergic neurotransmission by uptake inhibition. Lofepramine may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. Lofepramine has significant anxiolytic efficacy in addition to its antidepressant properties. Lofepramine chemical structure
  4. BCC7660 LY 393558 271780-64-4 LY 393558 chemical structure
  5. BCC7267 (±)-McN 5652 Potent, orally active 5-HT uptake inhibitor. Also inhibits noradrenalin and dopamine uptake <em>in vitro</em> (±)-McN 5652 chemical structure
  6. BCC5965 (±)-MDMA hydrochloride 92279-84-0 (±)-MDMA hydrochloride chemical structure
  7. BCC6183 Mephedrone hydrochloride 1189726-22-4 Mephedrone hydrochloride chemical structure
  8. BCC4922 Milnacipran HCl Milnacipran hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia. Milnacipran HCl chemical structure
  9. BCC7479 Nefazodone hydrochloride Nefazodone hydrochloride is an antidepressant drug. Nefazodone hydrochloride chemical structure
  10. BCC7265 Paroxetine maleate 64006-44-6 Paroxetine maleate chemical structure
  11. BCC5059 Sertraline HCl Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. Sertraline HCl chemical structure

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