Neural Development
Neural development describes the growth and development of the nervous system starting from embryogenesis and continuing throughout life.
Neural Development Products Targets
- FGFR (5)
- GABAB Receptor (28)
- Others (13)
- Stem Cell Signaling (27)
- Stem Cell Proliferation (25)
- Reprogramming (17)
- Nucleoside Transporter (5)
- Glycine Transporter (6)
- GABA (10)
- Cannabinoid Transporter (10)
- Acetylcholine Transporter (1)
- D4 Receptor (12)
- PORCN (4)
- beta-catenin (13)
- Casein Kinase 1 (7)
- 5-HT7 Receptor (11)
- 5-HT6 Receptor (14)
- 5-ht5 Receptor (2)
- 5-HT4 Receptor (17)
- NOP Receptor (21)
- Mu-Opioid Receptors (15)
- Kappa Opioid Receptors (14)
- AMPA Receptor (45)
- GABAA-ρ Receptor (8)
- GABAA Receptor (66)
- GPR55 (8)
- CB2 Receptor (6)
- CB1 Receptor (17)
- Nicotinic (α7) Receptor (25)
- Nicotinic (α4β2) Receptor (14)
- D3 Receptor (12)
- Vesicular Monoamine Transporter (4)
- NMDA Receptor (87)
- Kainate Receptor (22)
- D2 Receptor (14)
- D1 and D5 Receptor (16)
- Glutamate Transporter (18)
- Dopamine Transporter (20)
- Tankyrase (5)
- Adrenergic Transporter (23)
- 5-HT Transporter (30)
- nNOS (5)
- iNOS (11)
- eNOS (1)
- Stem Cell Differentiation (54)
- Delta opioid receptor (16)
- Adrenergic α2 Receptor (33)
- Adrenergic α1 Receptor (22)
- Adrenergic β3 Receptor (12)
- Adrenergic β2 Receptor (6)
- Adrenergic β1 Receptor (7)
- Hedgehog Signaling (15)
- Cancer Stem Cell (9)
Products for Neural Development - Page 58
- Cat.No. Product Name Information/Activity
-
BCC6556
Dihydrokainic acid
52497-36-6
-
BCC7295
(±)-HIP-B
227619-65-0
-
BCC6565
L-(-)-threo-3-Hydroxyaspartic acid
7298-99-9
-
BCC6804
(±)-threo-3-Methylglutamic acid
63088-04-0
-
BCC6873
MPDC
MPDC is a potent and competitive inhibitor of the Na+-dependent high-affinity glutamate transporter in forebrain synaptosomes.
-
BCC6595
L-trans-2,4-PDC
64769-66-0
-
BCC5735
DL-TBOA
DL-TBOA is a potent non-transportable inhibitor of excitatory amino acid transporters with IC50s of 70 μM, 6 μM and 6 μM for excitatory amino acid transporter-1 (EAAT1), EAAT2 and EAAT3, respectively. DL-TBOA inhibits the uptake of [14C]glutamate in COS-1 cells expressing the human EAAT1 and EAAT2 with Ki valuesof 42 μM and 5.7 μM, respectively. DL-TBOA blocks EAAT4 and EAAT5 in a competitive manner with Ki values of 4.4 μM and 3.2 μM, respectively.
-
BCC5919
TFB-TBOA
480439-73-4
-
BCC7692
UCPH 101
UCPH-101 is an excitatory amino acid transporter subtype 1 (EAAT1) inhibitor with an IC50 of 0.66 μM.
-
BCC7442
WAY 213613
WAY-213613 is a potent, selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 with IC50 of 85 nM EAAT2. It displays 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s are 5 and 3.8 μM, respectively). WAY-213613 shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function.
