Schizophrenia Research

Schizophrenia is a chronic, debilitating mental disorder affecting 1-2% of the global population. Symptoms are split into two types; 'positive' symptoms, including delusions and hallucinations, and 'negative' symptoms, including anhedonia and lack of motivation. Studies suggest that genetics, early environment, neurobiology, psychological and social processes are important contributory factors; some recreational and prescription drugs appear to cause or worsen symptoms. Several neurobiological alterations in brain structure, physiology and neurochemistry have been documented, along with an ever-increasing list of susceptibility genes.

Schizophrenia Research Products Targets

Products for Schizophrenia Research - Page 34

  1. Cat.No. Product Name Information/Activity
  2. BCC6341 4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1,4-dihydropyrrolo[3,4-d]pyrazol-5-yl]benzoic acid CID 16020046 is a potent and selective GPR55(LPI receptor) antagonist; inhibitsGPR55 constitutive activity with IC50 of 0.15 uM. 4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1,4-dihydropyrrolo[3,4-d]pyrazol-5-yl]benzoic acid chemical structure
  3. BCC7104 A 68930 hydrochloride Potent, selective D<sub>1</sub>-like agonist A 68930 hydrochloride chemical structure
  4. BCC7159 A 77636 hydrochloride Potent, selective D<sub>1</sub>-like agonist. Orally active A 77636 hydrochloride chemical structure
  5. BCC7250 (R)-(-)-Apomorphine hydrochloride 314-19-2 (R)-(-)-Apomorphine hydrochloride chemical structure
  6. BCC6991 CY 208-243 CY 208-243 is a selective dopamine D1 receptor agonist which exhibits antiparkinsonian activity. CY 208-243 chemical structure
  7. BCC5681 Dihydrexidine hydrochloride (+)-Dihydrexidine hydrochloride ((+)-DAR-0100 hydrochloride) is a dopamine D1 receptor agonist with an EC50 of 72± 21 nM. Dihydrexidine hydrochloride chemical structure
  8. BCC7837 NPEC-caged-dopamine 1257326-23-0 NPEC-caged-dopamine chemical structure
  9. BCC6848 SKF 38393 hydrobromide 20012-10-6 SKF 38393 hydrobromide chemical structure
  10. BCC7144 SKF 77434 hydrobromide 300561-58-4 SKF 77434 hydrobromide chemical structure
  11. BCC7071 SKF 81297 hydrobromide 67287-39-2 SKF 81297 hydrobromide chemical structure

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