NPY Receptors - GPCR/G protein

Cat.No. Product Name Information

BCC7456 BIBP 3226 trifluoroacetate BIBP3226 TFA is a potent and selective neuropeptide Y Y1 (NPY Y1) and neuropeptide FF (NPFF) receptor antagonist, with Kis of 1.1, 79, and 108 nM for rNPY Y1, hNPFF2, and rNPFF, respectively. BIBP3226 TFA displays anxiogenic-like effect.

BCC6959 Neuropeptide Y 13-36 (porcine)

BCC5716 [Leu31,Pro34]-Neuropeptide Y (porcine)

BCC5722 [Leu31,Pro34]-Neuropeptide Y (human, rat)

BCC6238 CYM 9484 CYM 9484 is a selective and highly potent neuropeptide Y (NPY) Y2 receptor antagonist with an IC50 value of 19 nM.

BCC7690 [D-Trp34]-Neuropeptide Y

BCC7085 GR 231118

BCC5865 BWX 46 Highly selective NPY Y5 agonist BWX 46

BCC7284 PD 160170

BCC7355 BIBO 3304 trifluoroacetate BIBO3304 TFA is a potent, orally active, and selective neuropeptide Y (NPY) Y1 receptor antagonist, with subnanomolar affinity for both the human and the rat Y1 receptor (IC50=0.38 and 0.72 nM, respectively).

BCC7270 NTNCB hydrochloride

BCC7283 CGP 71683 hydrochloride CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes.

BCC7158 BIIE 0246 BIIE-0246 is a potent and highly selective non-peptide neuropeptide Y (NPY) Y2 receptor antagonist, with an IC50 of 15 nM.

BCC5882 BVD 10 Highly selective NPY Y1 receptor antagonist; devoid of Y4 agonist activity BVD 10

BCC7687 S 25585 S 25585

BCC7708 LU AA33810

BCC5750 [cPP1-7,NPY19-23,Ala31,Aib32,Gln34] - hPancreatic Polypeptide

BCC7747 NPY 5RA972

BCC7805 SF 11 SF 11

BCC7041 L-152,804 L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure.

BCC7613 BMS 193885 Potent, competitive NPY Y1 receptor antagonist

BCC6100 JNJ 5207787 JNJ-5207787 is a nonpeptidic, selective and penetrate the blood-brain barrier neuropeptide Y Y2 receptor (Y2) antagonist. JNJ-5207787 inhibits the binding of peptide YY (PYY) with pIC50s of 7.0 and 7.1 for human Y2 receptor and rat Y2 receptor, respectively. JNJ-5207787 is >100-fold selective versus human Y1, Y4, and Y5 receptors. JNJ 5207787

BCC5711 Pancreatic Polypeptide (human) Pancreatic Polypeptide, human is a C-terminally amidated 36 amino acid peptide, which acts as a neuropeptide Y (NPY) Y4/Y5 receptor agonist.

Products for NPY Receptors